Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589752 | 0.76 | BRD4 (0.34) | KDM4EPOLBLMNAMAPTALDH1A1 | |
| SCHEMBL1144954 | 0.67 | LMNA (0.35) | ERN1KDM4EPOLBLMNAMAPT | |
| SCHEMBL5154751 | 0.63 | CA12 (0.47) | KDM4ELMNACA12CA1CA2 | |
| SCHEMBL5156208 | 0.63 | ALDH1A1 (0.41) | KDM4EPOLBLMNAMAPTCA12 | |
| SCHEMBL16921627 | 0.62 | MAPT (0.36) | KDM4EPOLBLMNAMAPTCYP2C9 | |
| SCHEMBL2384938 | 0.62 | BRD4 (0.35) | KDM4ELMNAMAPTCYP2C9ALDH1A1 | |
| SCHEMBL31405408 | 0.62 | CA12 (0.55) | KDM4ELMNAMAPTCYP2C9CA12 | |
| SCHEMBL7586824 | 0.62 | KDM4E (0.35) | KDM4EPOLBMAPTCYP2C9SMN1; SMN2 | |
| SCHEMBL23900422 | 0.58 | BRD4 (0.54) | KDM4EPOLBLMNAMAPTALDH1A1 | |
| SCHEMBL17372112 | 0.58 | GRIN2D (0.42) | KDM4ELMNAMAPTCYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092038-A4 | OCT1p, A PROTEIN HAVING HOMOLOGY TO THE ORGANIC AND SUGAR TRANSPORTER FAMILY OF PROTEINS, AND USES THEREOF | MILLENNIUM PHARM INC (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-1092038-A1 | OCT1p, A PROTEIN HAVING HOMOLOGY TO THE ORGANIC AND SUGAR TRANSPORTER FAMILY OF PROTEINS, AND USES THEREOF | Millennium Pharmaceuticals, Inc. (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000000633-A1 | OCT1p, A PROTEIN HAVING HOMOLOGY TO THE ORGANIC AND SUGAR TRANSPORTER FAMILY OF PROTEINS, AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2000-01-06 | — | — | WO | disclosed |