Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.49 |
| ▸ | PPARD | Q03181 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7441783 | 0.79 | HTR6 (0.71) | HTR6PPARDPPARAPPARG | |
| Trifluoroacetic Acid SCHEMBL7322133 | 0.75 | HTR6 (0.62) | HTR6PPARDPPARAPPARG | |
| Trifluoroacetic Acid SCHEMBL7312234 | 0.73 | HTR6 (0.51) | HTR6PPARDPPARAPPARGEGFR | |
| SCHEMBL3034948 | 0.73 | HTR6 (0.74) | HTR6PPARDPPARAPPARG | |
| Oxalic Acid SCHEMBL7430614 | 0.73 | HTR6 (0.71) | HTR6PPARDPPARAPPARG | |
| Trifluoroacetic Acid SCHEMBL7318370 | 0.72 | HTR6 (0.49) | HTR6PPARDPPARAPPARG | |
| Trifluoroacetic Acid SCHEMBL7317627 | 0.71 | EGFR (0.55) | PPARDPPARAPPARGEGFRIGF1R | |
| Trifluoroacetic Acid SCHEMBL7310320 | 0.71 | HTR6 (0.62) | HTR6PPARDPPARAPPARG | |
| Trifluoroacetic Acid SCHEMBL7320899 | 0.70 | SERPINE1 (0.33) | HTR6PPARG | |
| SCHEMBL3037803 | 0.70 | HTR6 (0.74) | HTR6PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020004198-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2002-01-10 | — | — | US | disclosed |