Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.62 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | PPARD | Q03181 | 3/20 | 0.56 |
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | HTR1E | P28566 | 1/20 | 0.49 |
| ▸ | HTR1F | P30939 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7310320 | 0.89 | HTR6 (0.62) | HTR6PPARGPPARDPPARAHTR1A | |
| Trifluoroacetic Acid SCHEMBL7318370 | 0.89 | HTR6 (0.49) | HTR6PPARGPPARDPPARA | |
| Trifluoroacetic Acid SCHEMBL7312234 | 0.83 | HTR6 (0.51) | HTR6PPARGPPARDPPARA | |
| Oxalic Acid SCHEMBL7430614 | 0.80 | HTR6 (0.71) | HTR6PPARGPPARDPPARAHTR1A | |
| Hydrochloric Acid SCHEMBL7437799 | 0.79 | HTR6 (0.78) | HTR6PPARGPPARDPPARAHTR1A | |
| Trifluoroacetic Acid SCHEMBL7317627 | 0.79 | EGFR (0.55) | PPARGPPARDPPARA | |
| SCHEMBL3029685 | 0.78 | PPARG (0.78) | HTR6PPARGPPARDPPARAHTR1A | |
| SCHEMBL5502012 | 0.78 | HTR6 (1.00) | HTR6PPARGPPARDPPARAHTR1A | |
| SCHEMBL13940270 | 0.77 | PPARG (0.80) | HTR6PPARGPPARDPPARAHTR1A | |
| Hydrochloric Acid SCHEMBL7438828 | 0.77 | HTR6 (0.98) | HTR6PPARGPPARDPPARAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | CTSL, MMP8, SERPINB1 | HTR6 4503/4885PPARG 2889/4885PPARD 1737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.