Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | GCKR | Q14397 | 7/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7313830 | 0.76 | PTGDR (0.45) | HTR6PPARGALDH1A1PKMPTGDR2 | |
| Trifluoroacetic Acid SCHEMBL7307520 | 0.72 | PTGDR2 (0.38) | HTR6PPARGPTGDR2 | |
| Trifluoroacetic Acid SCHEMBL7549610 | 0.71 | TP53 (0.32) | SCN5ASCN9AALDH1A1MAPTTP53 | |
| Trifluoroacetic Acid SCHEMBL7307842 | 0.71 | PTGDR (0.43) | HTR6PPARGALDH1A1PTGDR2 | |
| Trifluoroacetic Acid SCHEMBL7397740 | 0.69 | MALT1 (0.31) | ALDH1A1MAPTTP53 | |
| Trifluoroacetic Acid SCHEMBL7312753 | 0.66 | MDM2 (0.39) | SERPINE1PPARGPTGDR2 | |
| Trifluoroacetic Acid SCHEMBL7318205 | 0.65 | ICMT (0.41) | PPARG | |
| Trifluoroacetic Acid SCHEMBL7316949 | 0.62 | ABCB11 (0.40) | — | |
| Oxalic Acid SCHEMBL7441783 | 0.61 | HTR6 (0.71) | HTR6PPARG | |
| Trifluoroacetic Acid SCHEMBL6177349 | 0.59 | HTR6 (0.47) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | claimed |
| WO-2001034146-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | claimed |
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION | 2001-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010007877-A1 | NOVEL ANTI-INFECTIVES | CTSL, MMP8, SERPINB1 | SERPINE1 624/4885HTR6 4503/4885SCN5A 4840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.