Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NR2E3 | Q9Y5X4 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 4/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL7588227 | 0.99 | MAPT (0.51) | MAPTMEN1KMT2AALDH1A1PPARG | |
| SCHEMBL7855338 | 0.86 | CYP11B2 (0.48) | MAPTMEN1KMT2AALDH1A1PPARG | |
| SCHEMBL7584938 | 0.85 | CYP11B2 (0.47) | LMNACYP11B2CYP11B1TBXAS1 | |
| SCHEMBL7588234 | 0.81 | ALDH1A1 (0.43) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL15074528 | 0.75 | MAPK1 (0.51) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7590158 | 0.74 | CYP11B2 (0.56) | ALDH1A1KDM4EMAPK1CYP11B2CYP11B1 | |
| SCHEMBL7587012 | 0.73 | MKNK1 (0.46) | MAPTMEN1KMT2AALDH1A1PPARG | |
| SCHEMBL27860649 | 0.72 | IDO1 (0.52) | MAPTMEN1KMT2AALDH1A1PPARG | |
| SCHEMBL7589148 | 0.71 | CYP11B2 (0.48) | ALDH1A1KDM4EIDO1CYP11B2CYP11B1 | |
| SCHEMBL7953609 | 0.71 | MEN1 (0.53) | MAPTMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020006380-A1 | Pyrrole derivatives, their preparation and pharmaceutical compositions containing them | MIGNANI SERGE (FR) | 2002-01-17 | — | — | US | claimed |
| US-20020006380-A1 | Pyrrole derivatives, their preparation and pharmaceutical compositions containing them | MIGNANI SERGE (FR) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020006380-A1 | Pyrrole derivatives, their preparation and pharmaceutical compositions containing them | TNF, IL2, ZC3HAV1 | MAPT 3699/4885MEN1 4597/4885KMT2A 3711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.