Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951763 | 0.87 | MEN1 (0.48) | MEN1KMT2AGFERALDH1A1MAPT | |
| SCHEMBL10743662 | 0.86 | LMNA (0.42) | MEN1KMT2AGFERCYP11B2 | |
| SCHEMBL7585895 | 0.80 | KMT2A (0.56) | MEN1KMT2AUSP2ALDH1A1SLC2A1 | |
| SCHEMBL7946516 | 0.79 | NPC1 (0.36) | MEN1KMT2AGFERALDH1A1NPC1 | |
| SCHEMBL7953590 | 0.75 | CYP11B2 (0.44) | ALDH1A1MAPTSMN1; SMN2HSD17B10CYP11B1 | |
| SCHEMBL10736745 | 0.75 | KMT2A (0.44) | MEN1KMT2AGFERCYP11B2RXFP1 | |
| SCHEMBL7963752 | 0.75 | SLC2A1 (0.39) | MEN1KMT2AUSP2ALDH1A1SLC2A1 | |
| SCHEMBL7957240 | 0.73 | MKNK1 (0.39) | MEN1KMT2AGFERALDH1A1HSD17B10 | |
| SCHEMBL7964717 | 0.73 | ALDH1A1 (0.40) | MEN1KMT2AUSP2ALDH1A1SLC2A1 | |
| SCHEMBL7586850 | 0.71 | MAPT (0.52) | MEN1KMT2AUSP2ALDH1A1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194426-B1 | CONTROLLING TUMOR NECROSIS FACTOR | RHONA-POULENC RORER S.A. (FR) | 2001-02-27 | — | — | US | disclosed |