Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 11/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | C5AR1 | P21730 | 7/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482744 | 0.87 | CYP3A4 (0.52) | OPRL1OPRM1OPRD1OPRK1C5AR1 | |
| SCHEMBL8060424 | 0.85 | OPRL1 (0.60) | OPRL1OPRM1OPRD1OPRK1C5AR1 | |
| SCHEMBL8059497 | 0.82 | OPRL1 (0.48) | OPRL1OPRM1OPRD1OPRK1C5AR1 | |
| SCHEMBL14417274 | 0.82 | KDM4E (0.55) | OPRL1OPRM1OPRD1 | |
| SCHEMBL14515131 | 0.81 | CTSS (0.43) | OPRL1OPRM1OPRD1C5AR1 | |
| SCHEMBL14515137 | 0.80 | CYP3A4 (0.57) | OPRL1OPRM1C5AR1CYP3A4 | |
| SCHEMBL8478720 | 0.80 | CACNA1G (0.52) | OPRL1OPRM1OPRK1C5AR1CACNA1G | |
| SCHEMBL8058238 | 0.80 | CACNA1G (0.48) | OPRL1OPRM1OPRK1C5AR1CACNA1G | |
| SCHEMBL5389259 | 0.80 | C5AR1 (0.62) | OPRL1OPRM1OPRD1OPRK1C5AR1 | |
| SCHEMBL14198897 | 0.80 | OPRL1 (0.43) | OPRL1OPRM1OPRK1C5AR1CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100861-A1 | 1-(3-PHENYLOXYPROPYL)PIPERIDINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2002-12-19 | — | — | WO | disclosed |