Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 8/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | PRKCB | P05771 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCH | P24723 | 1/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8063089 | 0.88 | OPRM1 (0.50) | OPRL1OPRM1CYP3A4CACNA1GCACNA1H | |
| SCHEMBL7596262 | 0.87 | OPRM1 (0.49) | OPRL1OPRM1CYP3A4CACNA1GCACNA1H | |
| SCHEMBL6581954 | 0.86 | OPRL1 (0.54) | OPRL1OPRM1CYP3A4CACNA1GCACNA1H | |
| SCHEMBL3098947 | 0.86 | CYP2D6 (0.57) | OPRL1OPRM1CYP3A4CACNA1GCACNA1H | |
| SCHEMBL4703256 | 0.85 | CACNA1G (0.52) | OPRL1OPRM1CYP3A4CACNA1GCACNA1H | |
| SCHEMBL27194852 | 0.84 | CYP3A4 (0.53) | OPRL1OPRM1CYP3A4CACNA1GCACNA1H | |
| SCHEMBL8103415 | 0.83 | OPRL1 (0.53) | OPRL1OPRM1CACNA1GCACNA1HGPR119 | |
| SCHEMBL24709345 | 0.83 | CACNA1G (0.66) | OPRL1OPRM1CYP3A4CACNA1GCACNA1H | |
| SCHEMBL30849340 | 0.83 | CACNA1G (0.66) | OPRL1OPRM1CYP3A4CACNA1GCACNA1H | |
| SCHEMBL12919539 | 0.83 | CYP3A4 (0.58) | OPRL1OPRM1CYP3A4CACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100861-A1 | 1-(3-PHENYLOXYPROPYL)PIPERIDINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2002-12-19 | — | — | WO | disclosed |