Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | TYK2 | P29597 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543491 | 1.00 | HTR2C (0.48) | HTR2CHTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL2553028 | 1.00 | HTR2C (0.48) | HTR2CHTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL5987890 | 0.88 | HTR2A (0.55) | HTR2CHTR1AHTR1DHTR1BHTR2A | |
| Hydrochloric Acid SCHEMBL5989450 | 0.87 | HTR1A (0.54) | HTR2CHTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL27577588 | 0.80 | MAPK1 (0.46) | HTR2CHTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL176792 | 0.79 | PDPK1 (0.54) | PDPK1HSP90AB1ESR1JAK1JAK2 | |
| SCHEMBL27595583 | 0.78 | PRKAB2 (0.46) | HTR2CHTR1AHTR1DHTR1BHTR2A | |
| Hydrochloric Acid SCHEMBL177126 | 0.78 | PDPK1 (0.53) | PDPK1HSP90AB1ESR1JAK1JAK2 | |
| SCHEMBL5989957 | 0.78 | SLC6A2 (0.50) | HTR2CHTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL30166149 | 0.78 | SLC6A2 (0.50) | HTR2CHTR1AHTR1DHTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002098861-A1 | METHODS OF MAKING 1-(2-AMINOPROPYL)-6-HYDROXYINDAZOLE | ALCON, INC. (CH) | 2002-12-12 | — | — | WO | disclosed |