Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 5/20 | 0.52 |
| ▸ | RARB | P10826 | 5/20 | 0.52 |
| ▸ | RARG | P13631 | 5/20 | 0.52 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.51 |
| ▸ | CYP26B1 | Q9NR63 | 5/20 | 0.51 |
| ▸ | RXRA | P19793 | 9/20 | 0.50 |
| ▸ | RXRB | P28702 | 7/20 | 0.50 |
| ▸ | RXRG | P48443 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | BLVRB | P30043 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8341287 | 0.85 | RARA (0.45) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL8337872 | 0.85 | RARA (0.45) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL8336498 | 0.81 | RXRA (0.47) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL8529268 | 0.80 | RXRA (0.58) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL18786579 | 0.77 | RXRA (0.52) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL29605538 | 0.75 | CYP26B1 (0.83) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL21776768 | 0.75 | CYP26B1 (0.83) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL8795908 | 0.73 | CYP26B1 (0.51) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL9586582 | 0.72 | CYP26B1 (0.70) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL9208986 | 0.72 | RXRA (0.78) | RARARARBRARGCYP26A1CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020082419-A1 | 2,4-pentadienoic acid derivatives having retinoid-like biological activity | ALLERGAN SALES, INC. | 2002-06-27 | — | — | US | disclosed |
| WO-1999008992-A1 | 2,4-PENTADIENOIC ACID DERIVATIVES HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN SALES, INC. (US) | 1999-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020082419-A1 | 2,4-pentadienoic acid derivatives having retinoid-like biological activity | RXRA, RXRB, CBR1 | RARA 6/4885RARB 13/4885RARG 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.