Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 9/20 | 0.58 |
| ▸ | RARA | P10276 | 4/20 | 0.58 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.54 |
| ▸ | CYP26B1 | Q9NR63 | 5/20 | 0.54 |
| ▸ | RXRG | P48443 | 7/20 | 0.53 |
| ▸ | RXRB | P28702 | 5/20 | 0.53 |
| ▸ | RARB | P10826 | 3/20 | 0.52 |
| ▸ | RARG | P13631 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18786579 | 0.91 | RXRA (0.52) | RXRARARACYP26A1CYP26B1RXRG | |
| SCHEMBL7899456 | 0.83 | CYP26B1 (0.46) | RXRARARACYP26A1CYP26B1RXRG | |
| SCHEMBL8795417 | 0.81 | PLA2G4A (0.50) | RXRARARACYP26A1CYP26B1RXRG | |
| SCHEMBL9256306 | 0.81 | PLA2G4A (0.50) | RXRARARACYP26A1CYP26B1RXRG | |
| SCHEMBL9256311 | 0.81 | PLA2G4A (0.50) | RXRARARACYP26A1CYP26B1RXRG | |
| SCHEMBL8795020 | 0.81 | PLA2G4A (0.50) | RXRARARACYP26A1CYP26B1RXRG | |
| SCHEMBL7587462 | 0.80 | RARA (0.52) | RXRARARACYP26A1CYP26B1RXRG | |
| SCHEMBL8795908 | 0.79 | CYP26B1 (0.51) | RXRARARACYP26A1CYP26B1RXRG | |
| SCHEMBL9256485 | 0.79 | RXRA (0.49) | RXRARARACYP26A1CYP26B1RXRG | |
| SCHEMBL8796066 | 0.79 | RXRA (0.49) | RXRARARACYP26A1CYP26B1RXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915823-A1 | BI-AROMATIC COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998022423-A1 | BI-AROMATIC COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-05-28 | — | — | WO | disclosed |