Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL6864303 | 0.97 | TSHR (0.63) | TSHRTP53SRD5A2CA1CA2 | |
| Benzoic Acid SCHEMBL6347261 | 0.90 | TSHR (0.70) | TSHRTP53SRD5A2CA1CA2 | |
| Isonicotinic Acid SCHEMBL6782562 | 0.84 | NAPRT (0.74) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL31248123 | 0.82 | TSHR (0.86) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1655 | 0.82 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.82 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 0.82 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL175823 | 0.82 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Isophthalic Acid SCHEMBL6657098 | 0.80 | CA12 (0.56) | TSHRTP53CA1CA2CA12 | |
| Isophthalic Acid SCHEMBL6859593 | 0.79 | CA12 (0.54) | TSHRTP53CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110809599-B | Thermoplastic polyester elastomer resin foam molded body and method for producing same | 东洋纺株式会社 | 2021-12-07 | — | — | CN | disclosed |
| CN-110809599-A | Thermoplastic polyester elastomer resin foam molded body and method for producing same | 东洋纺株式会社 | 2020-02-18 | — | — | CN | disclosed |
| EP-0711658-B1 | Multi-layer molded article and method for producing the same | SUMITOMO CHEMICAL CO (JP) | 2002-10-23 | — | — | EP | disclosed |
| US-6045732-A | HAVING A SPECIFIC ADHESIVE LAYER BETWEEN A VINYL CHLORIDE RESIN SKIN MATERIAL LAYER AND A PROPYLENE RESIN CORE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0711658-A2 | Multi-layer molded article and method for producing the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5183873-A | Curing to solid elastomers | WACKER SILICONES CORPORATION (US) | 1993-02-02 | — | — | US | disclosed |
| US-4230820-A | WITHOUT THE ADDITION OF AN EXTERNAL BLOWING AGENT | WACKER-CHEMIE GMBH (DE) | 1980-10-28 | — | — | US | disclosed |