SCHEMBL7587637

SCHEMBL7587637

c1ccc(-c2ccc(-c3ccc(-c4cccs4)s3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.50
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
LTA4H P09960 2/20 0.47
POLB P06746 2/20 0.47
RAB9A P51151 2/20 0.47
NQO2 P16083 1/20 0.46
HSD17B1 P14061 1/20 0.46
HSD17B2 P37059 1/20 0.46
ALDH1A1 P00352 3/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
KDM4E B2RXH2 3/20 0.44
MAPT P10636 3/20 0.44
LMNA P02545 2/20 0.44
GAA P10253 2/20 0.44
GLA P06280 1/20 0.44
HPGD P15428 2/20 0.43
NPC1 O15118 1/20 0.43
TP53 P04637 1/20 0.43
NFKB1 P19838 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14960831 0.96 DPP4 (0.53) DPP4MEN1KMT2ALTA4HPOLB
SCHEMBL14960832 0.96 DPP4 (0.53) DPP4MEN1KMT2ALTA4HPOLB
SCHEMBL498361 0.96 DPP4 (0.53) DPP4MEN1KMT2ALTA4HPOLB
SCHEMBL7589651 0.96 DPP4 (0.53) DPP4MEN1KMT2ALTA4HPOLB
SCHEMBL14190036 0.85 LTA4H (0.59) DPP4MEN1KMT2ALTA4HALDH1A1
SCHEMBL559934 0.85 LTA4H (0.59) MEN1KMT2ALTA4HALDH1A1L3MBTL1
SCHEMBL7058736 0.85 LTA4H (0.59) MEN1KMT2ALTA4HALDH1A1L3MBTL1
SCHEMBL12408419 0.85 LTA4H (0.59) DPP4MEN1KMT2ALTA4HALDH1A1
SCHEMBL29363583 0.85 LTA4H (0.59) DPP4MEN1KMT2ALTA4HALDH1A1
SCHEMBL13027924 0.85 RAB9A (0.59) MEN1KMT2APOLBRAB9ANQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130037843-A1 LIGHT EMITTING TRANSISTOR NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) 2013-02-14 US disclosed
US-20130037843-A1 LIGHT EMITTING TRANSISTOR NATIONAL UNIVERSITY CORPORATION KYOTO INSTITUTE OF TECHNOLOGY (JP) 2013-02-14 US disclosed
US-20020114973-A1 Molecular compound, luminous material using the same, and luminous element JAPAN CHEMICAL INNOVATION INSTITUTE (JP) 2002-08-22 US disclosed
US-6355365-B1 FOR USE IN ORGANIC ELECTRO LUMINESCENCE (EL) DEVICE; EFFICIENCY JAPAN CHEMICAL INNOVATION INSTITUTE (JP) 2002-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020114973-A1 Molecular compound, luminous material using the same, and luminous element TYR, BRD4, NOTCH1 DPP4 3917/4885MEN1 1513/4885KMT2A 512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.