Acifluorfen

Acifluorfen

SCHEMBL7588028

COC(=O)Nc1cccc(OC(=O)Nc2cccc(C)c2)c1.O=C(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.65
KMT2A Q03164 4/20 0.65
TDP1 Q9NUW8 3/20 0.65
TTR P02766 1/20 0.65
PPOX P50336 1/20 0.65
ALDH1A1 P00352 3/20 0.48
FAAH O00519 1/20 0.48
CYP3A4 P08684 1/20 0.48
MAPK1 P28482 1/20 0.48
MAPT P10636 4/20 0.44
LMNA P02545 5/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
PYGL P06737 1/20 0.43
POLB P06746 3/20 0.42
STK39 Q9UEW8 1/20 0.41
CCR6 P51684 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
GPR55 Q9Y2T6 1/20 0.41
AKR1B1 P15121 1/20 0.39
AKR1C4 P17516 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acifluorfen SCHEMBL7582925 0.89 TDP1 (0.64) MEN1KMT2ATDP1TTRPPOX
Phenmedipham SCHEMBL7578589 0.89 MEN1 (0.50) MEN1KMT2ATDP1TTRPPOX
Oxyfluorfen SCHEMBL7583027 0.88 MEN1 (0.48) MEN1KMT2ATDP1TTRPPOX
Phenmedipham SCHEMBL7586962 0.84 TDP1 (0.67) MEN1KMT2ATDP1TTRPPOX
Desmedipham SCHEMBL7577677 0.82 MEN1 (0.53) MEN1KMT2ATDP1TTRPPOX
Phenmedipham SCHEMBL7585413 0.82 FAAH (0.48) MEN1KMT2ATDP1TTRPPOX
Acifluorfen SCHEMBL7579211 0.81 TDP1 (0.72) MEN1KMT2ATDP1TTRPPOX
Acifluorfen SCHEMBL10542053 0.81 TDP1 (0.92) MEN1KMT2ATDP1TTRPPOX
Acifluorfen SCHEMBL29448829 0.80 TDP1 (1.00) MEN1KMT2ATDP1TTRPPOX
Acifluorfen SCHEMBL29445767 0.80 TDP1 (1.00) MEN1KMT2ATDP1TTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885KMT2A 2099/4885TDP1 1969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.