Carfentrazone-Ethyl

Carfentrazone-Ethyl

SCHEMBL7588034

CCOC(=O)C(Cl)Cc1cc(-n2nc(C)n(C(F)F)c2=O)c(F)cc1Cl.COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2Cl)n1.O=C(O)COc1ccc(Cl)c2cccnc12

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.34
PTGER4 P35408 1/20 0.32
AGTR1 P30556 1/20 0.30
AGTR2 P50052 1/20 0.30
PKM P14618 1/20 0.30
P2RY12 Q9H244 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carfentrazone-Ethyl SCHEMBL7577249 0.96 MAPT (0.33) KDM4ENPC1ALDH1A1MAPT
Carfentrazone-Ethyl SCHEMBL7581734 0.94 MAPT (0.33) KDM4ENPC1ALDH1A1MAPT
Prosulfuron SCHEMBL7580495 0.93 MAPT (0.32) KDM4ENPC1ALDH1A1MAPTPTGER4
Carfentrazone-Ethyl SCHEMBL7584831 0.92 MAPT (0.30) MAPT
Carfentrazone-Ethyl SCHEMBL7585687 0.92
Carfentrazone-Ethyl SCHEMBL7578433 0.89 KDM4E (0.42) KDM4ENPC1ALDH1A1MAPTAGTR1
Carfentrazone-Ethyl SCHEMBL7584078 0.88
Carfentrazone-Ethyl SCHEMBL7587466 0.88 MAPT (0.37) KDM4ENPC1ALDH1A1MAPTPKM
Carfentrazone-Ethyl SCHEMBL7597242 0.85 PKM (0.31) PKM
Carfentrazone-Ethyl SCHEMBL7582144 0.85 MAPT (0.38) KDM4ENPC1ALDH1A1MAPTAGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT KDM4E 1886/4885NPC1 4238/4885ALDH1A1 812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.