Fomesafen

Fomesafen

SCHEMBL7588428

CCNc1nc(Cl)nc(NCC)n1.CP(=O)(O)CCC(N)C(=O)O.CS(=O)(=O)NC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
TTR P02766 1/20 0.48
PPOX P50336 1/20 0.48
FFAR1 O14842 2/20 0.35
GRM8 O00222 8/20 0.35
GRM4 Q14833 8/20 0.35
GRM6 O15303 6/20 0.35
MRGPRX4 Q96LA9 1/20 0.35
FLT1 P17948 1/20 0.33
FLT4 P35916 1/20 0.33
KDR P35968 1/20 0.33
LMNA P02545 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
SCN9A Q15858 1/20 0.32
PPARG P37231 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fomesafen SCHEMBL7576308 0.97 TDP1 (0.45) TDP1MEN1KMT2ATTRPPOX
Fomesafen SCHEMBL7575755 0.94 TDP1 (0.42) TDP1MEN1KMT2ATTRPPOX
Acifluorfen SCHEMBL7581016 0.93 TDP1 (0.57) TDP1MEN1KMT2ATTRPPOX
Acifluorfen SCHEMBL7586534 0.89 TDP1 (0.53) TDP1MEN1KMT2ATTRPPOX
Acifluorfen SCHEMBL7580896 0.89 TDP1 (0.53) TDP1MEN1KMT2ATTRPPOX
Oxyfluorfen SCHEMBL7589088 0.88 MEN1 (0.45) TDP1MEN1KMT2ATTRPPOX
Lactofen SCHEMBL7578948 0.87 TDP1 (0.46) TDP1MEN1KMT2ATTRPPOX
Acifluorfen SCHEMBL7584131 0.87 TDP1 (0.50) TDP1MEN1KMT2ATTRPPOX
Fomesafen SCHEMBL7578127 0.85 TDP1 (0.53) TDP1MEN1KMT2ATTRPPOX
Fomesafen SCHEMBL7583167 0.85 TDP1 (0.50) TDP1MEN1KMT2ATTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.