Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596550 | 0.94 | KMT2A (0.51) | ALDH1A1KDM4EHPGDMAPK1PTK2B | |
| SCHEMBL4350011 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDMAPK1PTK2B | |
| SCHEMBL14403271 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDMAPK1PTK2B | |
| SCHEMBL7588981 | 0.76 | ALDH1A1 (0.64) | ALDH1A1HPGDKMT2A | |
| SCHEMBL11742060 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDMAPK1PTK2B | |
| SCHEMBL13510428 | 0.75 | MCL1 (0.60) | ALDH1A1KDM4EHPGDMAPK1PTK2B | |
| SCHEMBL14563534 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDMAPK1PTK2B | |
| SCHEMBL21495768 | 0.75 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDMAPK1PTK2B | |
| SCHEMBL22315270 | 0.75 | KMT2A (0.59) | ALDH1A1KDM4EHPGDMAPK1PTK2B | |
| SCHEMBL13853042 | 0.75 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDMAPK1PTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |