Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7589006 | 0.94 | ALDH1A1 (0.50) | KMT2AHPGDALDH1A1MAPK1PTK2B | |
| SCHEMBL633995 | 0.79 | KMT2A (0.76) | KMT2AHPGDPGRARALDH1A1 | |
| SCHEMBL4350011 | 0.75 | ALDH1A1 (0.47) | KMT2AHPGDALDH1A1ALOX15HSD17B10 | |
| SCHEMBL14403271 | 0.75 | ALDH1A1 (0.55) | KMT2AHPGDPGRALDH1A1MAPK1 | |
| SCHEMBL9186300 | 0.75 | KMT2A (0.70) | KMT2AHPGDPGRARALDH1A1 | |
| SCHEMBL11372811 | 0.73 | KMT2A (0.72) | KMT2AHPGDPGRARALDH1A1 | |
| SCHEMBL9479374 | 0.73 | KMT2A (0.72) | KMT2AHPGDPGRARALDH1A1 | |
| SCHEMBL4345454 | 0.73 | KMT2A (0.54) | KMT2AHPGDPGRARALDH1A1 | |
| SCHEMBL7588981 | 0.72 | ALDH1A1 (0.64) | KMT2AHPGDALDH1A1ALOX15HSD17B10 | |
| SCHEMBL11742060 | 0.71 | ALDH1A1 (0.52) | KMT2AHPGDPGRARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |