Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802397 | 0.83 | AKR1C3 (0.53) | AKR1C3AKR1C2CYP1A2CYP2A6PTGS1 | |
| SCHEMBL6798261 | 0.83 | AKR1C3 (0.53) | AKR1C3AKR1C2CYP1A2CYP2A6PTGS1 | |
| SCHEMBL6796335 | 0.82 | AKR1C3 (0.48) | AKR1C3AKR1C2CYP1A2CYP2A6PPARG | |
| SCHEMBL6803645 | 0.82 | AKR1C3 (0.48) | AKR1C3AKR1C2CYP1A2CYP2A6PPARG | |
| SCHEMBL8902344 | 0.78 | LDHA (0.57) | PPARGPPARAMMP1 | |
| SCHEMBL12419939 | 0.78 | ALDH1A1 (0.54) | AKR1C3AKR1C2CYP1A2CYP2A6MAPT | |
| SCHEMBL13577590 | 0.75 | CYP1A2 (0.54) | AKR1C3AKR1C2CYP1A2CYP2A6MAPT | |
| SCHEMBL7633821 | 0.74 | ABCB1 (0.57) | CYP1A2NPC1RAB9APPARGPPARA | |
| SCHEMBL6801906 | 0.74 | AKR1C3 (0.47) | AKR1C3AKR1C2CYP1A2CYP2A6MAPT | |
| SCHEMBL22624583 | 0.73 | SLC7A5 (0.45) | CYP1A2ABCB1LMNACYP3A4SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020169326-A1 | Esters and amides as PLA2 inhibitors | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 2002-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169326-A1 | Esters and amides as PLA2 inhibitors | PLA2G4A, PLA2G2D, PLA2G4B | AKR1C3 733/4885AKR1C2 728/4885CYP1A2 496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.