Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 3/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798261 | 0.76 | AKR1C3 (0.53) | AKR1C3AKR1C2CYP1A2CYP2A6MME | |
| SCHEMBL6802397 | 0.76 | AKR1C3 (0.53) | AKR1C3AKR1C2CYP1A2CYP2A6MME | |
| SCHEMBL27406942 | 0.74 | LDHA (0.67) | PPARGPPARAKMT2A | |
| SCHEMBL25719108 | 0.74 | AKR1C3 (1.00) | AKR1C3AKR1C2CYP1A2CYP2A6HTR2A | |
| SCHEMBL11461305 | 0.74 | AKR1C3 (1.00) | AKR1C3AKR1C2CYP1A2CYP2A6HTR2A | |
| SCHEMBL18770098 | 0.74 | AKR1C3 (1.00) | AKR1C3AKR1C2CYP1A2CYP2A6HTR2A | |
| SCHEMBL11827354 | 0.73 | PTGS1 (0.51) | AKR1C3AKR1C2HTR2APTGS2ALDH1A1 | |
| SCHEMBL9176689 | 0.73 | HTR2A (0.53) | AKR1C3AKR1C2CYP1A2CYP2A6PPARG | |
| SCHEMBL7589057 | 0.73 | AKR1C3 (0.46) | AKR1C3AKR1C2CYP1A2CYP2A6PPARG | |
| SCHEMBL14945003 | 0.72 | HTR2A (0.59) | AKR1C3AKR1C2CYP1A2CYP2A6MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020169326-A1 | Esters and amides as PLA2 inhibitors | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 2002-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169326-A1 | Esters and amides as PLA2 inhibitors | PLA2G4A, PLA2G2D, PLA2G4B | AKR1C3 733/4885AKR1C2 728/4885CYP1A2 496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.