Flumioxazin

Flumioxazin

SCHEMBL7589167

C#CCN1C(=O)COc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)cc21.CCOC(=O)COC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TTR P02766 1/20 0.41
PPOX P50336 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lactofen SCHEMBL7578370 0.92 TDP1 (0.40) TDP1MEN1KMT2ATTRPPOX
Flumioxazin SCHEMBL7578538 0.90 TDP1 (0.53) TDP1MEN1KMT2ATTRPPOX
Flumioxazin SCHEMBL7582975 0.88 PPOX (0.38) TDP1MEN1KMT2ATTRPPOX
Fomesafen SCHEMBL7583918 0.87 TDP1 (0.42) TDP1MEN1KMT2ATTRPPOX
Flumioxazin SCHEMBL7579443 0.85 TDP1 (0.51) TDP1MEN1KMT2ATTRPPOX
Flumipropyn SCHEMBL7587682 0.84 PPOX (0.44) TDP1MEN1KMT2ATTRPPOX
SCHEMBL7585747 0.82 MEN1 (0.36) TDP1MEN1KMT2ATTRPPOX
Flumiciorac-Pentyl SCHEMBL7575934 0.82 PPOX (0.44) TDP1MEN1KMT2ATTRPPOX
SCHEMBL38860 0.77 MEN1 (0.68) TDP1MEN1KMT2ATTRPPOX
Lactofen SCHEMBL7576882 0.77 PPOX (0.44) TDP1MEN1KMT2ATTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885KMT2A 2099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.