Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | BID | P55957 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.42 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582835 | 0.88 | HTT (0.43) | HTTLIPGTSHRBIDMCL1 | |
| SCHEMBL1545821 | 0.86 | HTT (0.49) | HTTLIPGTSHRBIDMCL1 | |
| SCHEMBL27362437 | 0.85 | LIPG (0.49) | HTTLIPGTSHRBIDMCL1 | |
| SCHEMBL4433080 | 0.84 | LIPG (0.51) | HTTLIPGTSHRBIDMCL1 | |
| SCHEMBL5509842 | 0.84 | F2R (0.50) | HTTTSHRALDH1A1ADRB2LMNA | |
| SCHEMBL15923268 | 0.83 | HTT (0.49) | HTTLIPGTSHRALDH1A1BID | |
| SCHEMBL1004433 | 0.82 | CYP3A4 (0.55) | LIPGTSHRALDH1A1BIDMCL1 | |
| SCHEMBL28960300 | 0.82 | PPARA (0.46) | HTTLIPGTSHRALDH1A1LMNA | |
| SCHEMBL3744047 | 0.82 | ALDH1A1 (0.66) | HTTALDH1A1ADRB2KDRLMNA | |
| SCHEMBL11039198 | 0.81 | LIPG (0.51) | HTTLIPGTSHRALDH1A1BID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944321-B1 | COMPOSITIONS FOR THE SYSTEMIC CONTROL OF PARASITES OF WARM-BLOODED ANIMALS | ISAGRO SPA (IT) | 2002-09-18 | — | — | EP | disclosed |
| US-6136836-A | A 1-(3-CHLORO-4-(1,1,2-TRIFLUORO-2-FLUOROMETHOXYETHOXY)PHENYL-3-(2,6-DIFLUOROBENZOYL)UREA | ISAGRO S.P.A. (IT) | 2000-10-24 | — | — | US | disclosed |