Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7593620 | 0.83 | HTR2B (0.38) | ABCB1HTR2BSIGMAR1HTR1AHTR7 | |
| SCHEMBL5856076 | 0.81 | HTR2B (0.34) | ABCB1HTR2BSIGMAR1HTR1AHTR7 | |
| SCHEMBL5857401 | 0.79 | HTR2B (0.33) | ABCB1HTR2BSIGMAR1HTR1AHTR7 | |
| SCHEMBL5855633 | 0.78 | ABCB1 (0.31) | ABCB1HTR2BSIGMAR1HTR1AESR1 | |
| SCHEMBL5855250 | 0.78 | CYP19A1 (0.35) | ABCB1HTR2BSIGMAR1HTR1AESR1 | |
| SCHEMBL5854838 | 0.76 | HTR1A (0.33) | ABCB1HTR2BSIGMAR1HTR1AALDH1A1 | |
| SCHEMBL7122199 | 0.76 | HTR2B (0.38) | ABCB1HTR2BSIGMAR1HTR1AHTR7 | |
| SCHEMBL7119227 | 0.76 | HTR2B (0.38) | ABCB1HTR2BSIGMAR1HTR1AHTR7 | |
| SCHEMBL5854576 | 0.76 | L3MBTL1 (0.34) | ABCB1HTR2BSIGMAR1HTR1A | |
| SCHEMBL5854274 | 0.76 | L3MBTL1 (0.34) | ABCB1HTR2BSIGMAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944613-B1 | BENZOPYRAN DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6153768-A | RECEPTOR BLOCKING ANTIESTROGENS HAVING REDUCED SIDE EFFECTS | C & C RESEARCH LABORATORIES (KR) | 2000-11-28 | — | — | US | disclosed |
| EP-0944613-A1 | NOVEL BENZOPYRAN DERIVATIVES | C & C Research Laboratories (KR) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025916-A1 | NOVEL BENZOPYRAN DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 1998-06-18 | — | — | WO | disclosed |