Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 2/20 | 0.33 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5856076 | 0.90 | HTR2B (0.34) | HTR2BSIGMAR1HTR1AHTR7TMEM97 | |
| SCHEMBL5857401 | 0.88 | HTR2B (0.33) | HTR2BSIGMAR1HTR1AHTR7TMEM97 | |
| SCHEMBL5854576 | 0.84 | L3MBTL1 (0.34) | HTR2BSIGMAR1HTR1AABCB1 | |
| SCHEMBL5854274 | 0.84 | L3MBTL1 (0.34) | HTR2BSIGMAR1HTR1AABCB1 | |
| SCHEMBL7589412 | 0.83 | ABCB1 (0.34) | HTR2BSIGMAR1HTR1AHTR7TMEM97 | |
| SCHEMBL7122199 | 0.79 | HTR2B (0.38) | HTR2BSIGMAR1HTR1AMAPTHTR7 | |
| SCHEMBL7119227 | 0.79 | HTR2B (0.38) | HTR2BSIGMAR1HTR1AMAPTHTR7 | |
| SCHEMBL5854210 | 0.78 | CTNNB1 (0.31) | — | |
| SCHEMBL5855633 | 0.76 | ABCB1 (0.31) | HTR2BSIGMAR1HTR1AABCB1 | |
| SCHEMBL7596943 | 0.74 | ESR1 (0.36) | HTR2BSIGMAR1TMEM97CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944613-B1 | BENZOPYRAN DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6153768-A | RECEPTOR BLOCKING ANTIESTROGENS HAVING REDUCED SIDE EFFECTS | C & C RESEARCH LABORATORIES (KR) | 2000-11-28 | — | — | US | disclosed |