Bifenox

Bifenox

SCHEMBL7589534

CCNc1nc(Cl)nc(NC(C)C)n1.CCc1cccc(C)c1N(C(=O)CCl)C(C)COC.COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-].CP(=O)(O)CCC(N)C(=O)O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
KDM4E B2RXH2 1/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bifenox SCHEMBL7582590 0.94 TDP1 (0.39) TDP1
Bifenox SCHEMBL7585133 0.92 TDP1 (0.47) TDP1KDM4ETP53MAPTTSHR
Bifenox SCHEMBL7580631 0.92 TDP1 (0.47) TDP1MAPTKMT2ANPSR1
Bifenox SCHEMBL7575784 0.90 TDP1 (0.32) TDP1
Metolachor SCHEMBL7579501 0.90 MEN1 (0.34) TDP1KMT2A
Lactofen SCHEMBL7578169 0.90 MEN1 (0.34) TDP1KMT2A
Bifenox SCHEMBL7583662 0.89 TDP1 (0.41) TDP1KDM4ETP53MAPTTSHR
Fomesafen SCHEMBL7586715 0.88 MEN1 (0.34) TDP1KMT2A
Oxyfluorfen SCHEMBL7588429 0.88 LMNA (0.33) TDP1MAPTKMT2A
Bifenox SCHEMBL7585017 0.88 TDP1 (0.40) TDP1KDM4ETP53MAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885KDM4E 1886/4885TP53 4303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.