Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | KLK7 | P49862 | 2/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150673 | 0.74 | GHSR (0.57) | GHSRTACR1 | |
| SCHEMBL5247053 | 0.74 | PPARA (0.59) | CTSLPPARAKLK7KLK5CTSS | |
| SCHEMBL5247044 | 0.74 | PPARA (0.59) | CTSLPPARAKLK7KLK5CTSS | |
| SCHEMBL7567562 | 0.74 | GHSR (0.59) | GHSRTACR1 | |
| SCHEMBL5247747 | 0.72 | PPARA (0.71) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL5227731 | 0.72 | PPARA (0.71) | PPARAKLK7KLK5CTSSPPARG | |
| SCHEMBL7572185 | 0.72 | GHSR (0.52) | GHSRPPARACTSSTACR1 | |
| Hydrochloric Acid SCHEMBL7571947 | 0.72 | GHSR (0.41) | GHSRCTSSTACR1 | |
| SCHEMBL8314876 | 0.72 | GHSR (0.49) | GHSRPPARAKLK7KLK5CTSS | |
| SCHEMBL7511586 | 0.72 | PPARA (0.40) | GHSRCTSLPPARAKLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994013696-A1 | SPIRO PIPERIDINES AND HOMOLOGS WHICH PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1994-06-23 | — | — | WO | disclosed |