SCHEMBL7589666

SCHEMBL7589666

CCCC(CCl)Oc1ccc(Oc2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 7/20 0.49
TSHR P16473 1/20 0.41
PPARG P37231 7/20 0.41
PPARA Q07869 7/20 0.41
LMNA P02545 2/20 0.40
ALDH1A1 P00352 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NR1H2 P55055 1/20 0.38
BAX Q07812 1/20 0.38
MAOA P21397 1/20 0.38
RNF4 P78317 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11035722 0.87 PPARG (0.35) PPARGPPARA
SCHEMBL7841888 0.83 SLC6A4 (0.43) LTA4HPPARGPPARALMNAMAOA
SCHEMBL11065085 0.80 PPARG (0.44) LTA4HTSHRPPARGPPARALMNA
SCHEMBL11673486 0.80 PPARG (0.38) LTA4HTSHRPPARGPPARALMNA
SCHEMBL28286594 0.79 LTA4H (0.42) LTA4HTSHRLMNAALDH1A1SMN1; SMN2
SCHEMBL27722727 0.79 LTA4H (0.42) LTA4HTSHRLMNAALDH1A1SMN1; SMN2
SCHEMBL11698189 0.77 LTA4H (0.50) LTA4HTSHRPPARGPPARALMNA
SCHEMBL23974956 0.77 PPARG (0.41) LTA4HPPARGPPARALMNAALDH1A1
SCHEMBL14844285 0.77 LTA4H (0.44) LTA4HPPARGPPARAMAOA
SCHEMBL8349925 0.77 SLC6A4 (0.39) LTA4HPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0944321-B1 COMPOSITIONS FOR THE SYSTEMIC CONTROL OF PARASITES OF WARM-BLOODED ANIMALS ISAGRO SPA (IT) 2002-09-18 EP claimed
US-6136836-A A 1-(3-CHLORO-4-(1,1,2-TRIFLUORO-2-FLUOROMETHOXYETHOXY)PHENYL-3-(2,6-DIFLUOROBENZOYL)UREA ISAGRO S.P.A. (IT) 2000-10-24 US claimed
US-4540711-A Method for combatting infestations of insects and acari, and compositions for use in said method MONTEDISON S.P.A. (IT) 1985-09-10 US claimed
US-4356329-A Hydroquinone ethers having juvenile hormone activity MONTEDISON S.P.A. (IT) 1982-10-26 US claimed
EP-0944321-B1 COMPOSITIONS FOR THE SYSTEMIC CONTROL OF PARASITES OF WARM-BLOODED ANIMALS ISAGRO SPA (IT) 2002-09-18 EP disclosed
US-6136836-A A 1-(3-CHLORO-4-(1,1,2-TRIFLUORO-2-FLUOROMETHOXYETHOXY)PHENYL-3-(2,6-DIFLUOROBENZOYL)UREA ISAGRO S.P.A. (IT) 2000-10-24 US disclosed
EP-0944321-A1 COMPOSITIONS FOR THE SYSTEMIC CONTROL OF PARASITES OF WARM-BLOODED ANIMALS ISAGRO S.p.A. (IT) 1999-09-29 EP disclosed
WO-1998025466-A1 COMPOSITIONS FOR THE SYSTEMIC CONTROL OF PARASITES OF WARM-BLOODED ANIMALS ISAGRO S.P.A. (IT) 1998-06-18 WO disclosed
US-4540711-A Method for combatting infestations of insects and acari, and compositions for use in said method MONTEDISON S.P.A. (IT) 1985-09-10 US disclosed
US-4356329-A Hydroquinone ethers having juvenile hormone activity MONTEDISON S.P.A. (IT) 1982-10-26 US disclosed