SCHEMBL11035722

SCHEMBL11035722

CCCC(CCl)Oc1ccc(OC(CCl)CCC)cc1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.35
PPARA Q07869 5/20 0.35
NQO1 P15559 1/20 0.33
TAS1R3 Q7RTX0 2/20 0.33
TAS1R1 Q7RTX1 2/20 0.33
MMP1 P03956 1/20 0.31
MMP13 P45452 1/20 0.31
SLC6A4 P31645 1/20 0.31
MAPT P10636 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7589666 0.87 LTA4H (0.49) PPARGPPARA
SCHEMBL20324943 0.80 CA1 (0.48) TAS1R3TAS1R1MMP1MMP13SLC6A4
SCHEMBL22644024 0.79 PPARA (0.43) PPARGPPARASLC6A4L3MBTL1
SCHEMBL28290605 0.78 TDP1 (0.48) MAPTL3MBTL1
SCHEMBL7841888 0.77 SLC6A4 (0.43) PPARGPPARASLC6A4MAPT
SCHEMBL10875297 0.77 L3MBTL1 (0.41) PPARGPPARASLC6A4L3MBTL1
SCHEMBL15871120 0.77 ACHE (0.38) PPARGPPARAMAPT
SCHEMBL5479203 0.77 PPARA (0.39) PPARGPPARASLC6A4L3MBTL1
SCHEMBL7409107 0.77 PPARA (0.39) PPARGPPARASLC6A4L3MBTL1
SCHEMBL5478715 0.77 PPARA (0.39) PPARGPPARASLC6A4L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4356329-A Hydroquinone ethers having juvenile hormone activity MONTEDISON S.P.A. (IT) 1982-10-26 US claimed
US-4540711-A Method for combatting infestations of insects and acari, and compositions for use in said method MONTEDISON S.P.A. (IT) 1985-09-10 US disclosed
US-4356329-A Hydroquinone ethers having juvenile hormone activity MONTEDISON S.P.A. (IT) 1982-10-26 US disclosed