SCHEMBL7589708

SCHEMBL7589708

CC(=O)Nc1nc(S)n[nH]1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPL P05186 5/20 0.50
SMN1; SMN2 Q16637 1/20 0.45
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
LMNA P02545 2/20 0.39
GDA Q9Y2T3 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
KDM4E B2RXH2 3/20 0.38
ADORA3 P0DMS8 2/20 0.37
ALOX15 P16050 3/20 0.35
HSD17B10 Q99714 3/20 0.35
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
ROCK2 O75116 1/20 0.33
ROCK1 Q13464 1/20 0.33
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31272024 0.78 ALPL (0.54) ALPLSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL31272534 0.76 ALPL (0.50) ALPLSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL15552380 0.74 ALPL (0.49) ALPLSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL29951924 0.73 ALPL (0.47) ALPLSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL9154861 0.72 ADORA2A (0.51) SMN1; SMN2MEN1KMT2ALMNAADORA3
SCHEMBL13760175 0.68 ADORA3 (0.55) ALPLSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL15551589 0.67 ALPL (0.49) ALPLSMN1; SMN2MEN1KMT2ALMNA
SCHEMBL11737243 0.66 POLB (0.52) ALPLKDM4EADORA3ALOX15HSD17B10
SCHEMBL8627227 0.65 LMNA (0.40) ALPLSMN1; SMN2LMNAGDACA1
SCHEMBL9818780 0.65 ALPL (0.43) ALPLSMN1; SMN2MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1251396-A2 Methods for making photothermographic emulsions and materials EASTMAN KODAK COMPANY (US) 2002-10-23 EP claimed
US-6413710-B1 USING ORGANONITROGEN RING COMPOUND EASTMAN KODAK COMPANY 2002-07-02 US claimed
EP-1251396-A2 Methods for making photothermographic emulsions and materials EASTMAN KODAK COMPANY (US) 2002-10-23 EP disclosed
US-6413710-B1 USING ORGANONITROGEN RING COMPOUND EASTMAN KODAK COMPANY 2002-07-02 US disclosed
US-5410065-A Preparation of 5-cylamino-1,2,4-triazole-3-sulfonamides DOWELANCO (US) 1995-04-25 US disclosed
US-5391759-A Preparation of 5-acylamino-1,2,4-triazole-3-sulfonamides DOWELANCO (US) 1995-02-21 US disclosed
EP-0401907-B1 Preparation of N-(3-(((aryl)amino)sulfonyl)-1H-1,2,4-triazol-5-yl)amines DOWELANCO (US) 1994-09-28 EP disclosed
EP-0375060-A1 Preparation of 5-acylamino-1,2,4-triazole-3-sulfonamides and intermediates THE DOW CHEMICAL COMPANY (US) 1990-06-27 EP disclosed
US-4937350-A Preparation of N-(-3(((aryl)amino)suldonyl)-1H-1,2,4-triazol-5-yl)amines THE DOW CHEMICAL COMPANY (US) 1990-06-26 US disclosed
US-4542094-A HYDROXYTETRAZAINDENES AND MERCAPTO-NITROGENCONTAINING HETEROCYLIC COMPOUNDS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1985-09-17 US disclosed
EP-0107488-A2 Silver halide emulsions KONICA CORPORATION (JP) 1984-05-02 EP disclosed