Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4282866 | 0.84 | ALDH1A1 (0.45) | HPGDALDH1A1POLBMAPTHSD17B10 | |
| SCHEMBL24359522 | 0.81 | GSTP1 (0.40) | HPGDALDH1A1POLBMAPTHSD17B10 | |
| SCHEMBL8310697 | 0.79 | KDM4E (0.47) | HPGDALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL1261902 | 0.78 | ALDH1A1 (0.36) | HPGDALDH1A1POLBMAPTHSD17B10 | |
| SCHEMBL5661170 | 0.75 | — | — | |
| SCHEMBL7589801 | 0.72 | ALDH1A1 (0.54) | HPGDALDH1A1POLBMAPTHSD17B10 | |
| SCHEMBL4279967 | 0.72 | FFAR1 (0.50) | HPGDALDH1A1POLBMAPTHSD17B10 | |
| SCHEMBL20528929 | 0.70 | KIF11 (0.41) | POLBL3MBTL1PTPN7KMT2AESR2 | |
| SCHEMBL11453438 | 0.70 | — | — | |
| SCHEMBL27528790 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811618-B1 | Furfurylthioalkanes, process for their preparation and use thereof | HAARMANN & REIMER GMBH (DE) | 2002-10-23 | — | — | EP | disclosed |
| US-6153770-A | ORGANOLEPTIC COMPOUNDS FOR FOOD AROMAS | HAARMANN & REIMER (DE) | 2000-11-28 | — | — | US | disclosed |
| EP-0811618-A1 | Furfurylthioalkanes, process for their preparation and use thereof | HAARMANN & REIMER GMBH (DE) | 1997-12-10 | — | — | EP | disclosed |