Pentachlorophenol

Pentachlorophenol

SCHEMBL7590198

COc1ccc(Cl)c(Cl)c1Cl.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 5/20 0.41
CYP3A4 P08684 2/20 0.41
AKR1B1 P15121 1/20 0.41
ALDH1A1 P00352 5/20 0.40
HPGD P15428 5/20 0.40
MAPT P10636 5/20 0.40
TSHR P16473 5/20 0.40
HSD17B10 Q99714 4/20 0.40
KMT2A Q03164 4/20 0.40
LMNA P02545 3/20 0.40
MEN1 O00255 2/20 0.40
HTR2A P28223 3/20 0.39
HTR2C P28335 3/20 0.39
HTR2B P41595 3/20 0.39
CLCN2 P51788 1/20 0.39
KDM4E B2RXH2 2/20 0.38
ALOX12 P18054 2/20 0.38
TP53 P04637 2/20 0.38
ALOX15 P16050 1/20 0.38
HIF1A Q16665 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL53547 0.87 ALDH1A1 (0.46) MAPK1CYP3A4ALDH1A1HPGDMAPT
SCHEMBL30715275 0.87 ALDH1A1 (0.46) MAPK1CYP3A4ALDH1A1HPGDMAPT
Hydrochloric Acid SCHEMBL11303156 0.83 ALDH1A1 (0.43) MAPK1CYP3A4ALDH1A1HPGDMAPT
SCHEMBL9814072 0.81 CLCN2 (0.41) MAPK1CYP3A4ALDH1A1HPGDMAPT
SCHEMBL9335491 0.81 MAPK1 (0.46) MAPK1CYP3A4AKR1B1ALDH1A1HPGD
SCHEMBL14339474 0.78 KDM4E (0.50) MAPK1CYP3A4ALDH1A1HPGDMAPT
SCHEMBL69364 0.74 MAPT (0.48) MAPK1CYP3A4ALDH1A1HPGDMAPT
SCHEMBL11151784 0.74 MAPK1 (0.48) MAPK1CYP3A4ALDH1A1HPGDMAPT
SCHEMBL28436581 0.72 HIF1A (0.53) MAPK1CYP3A4AKR1B1ALDH1A1HPGD
SCHEMBL8506369 0.72 AKR1B1 (0.68) MAPK1CYP3A4AKR1B1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1216123-A1 METHOD FOR TREATING CORK AND EXTRACTING ORGANIC COMPOUNDS FROM CORK, WITH A DENSE FLUID UNDER PRESSURE Commissariat à l'Energie Atomique (FR) 2002-06-26 EP disclosed
WO-2001023155-A1 METHOD FOR TREATING AND EXTRACTING CORK ORGANIC COMPOUNDS, WITH A DENSE FLUID UNDER PRESSURE COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2001-04-05 WO disclosed