SCHEMBL7590338

SCHEMBL7590338

N#Cc1ccc(-c2ccc(OCCCO)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 6/20 0.63
MMP3 P08254 5/20 0.60
HRH3 Q9Y5N1 10/20 0.58
HRH2 P25021 9/20 0.58
HRH1 P35367 9/20 0.58
MMP1 P03956 1/20 0.58
MMP9 P14780 1/20 0.58
MMP13 P45452 1/20 0.58
HDAC1 Q13547 1/20 0.57
HDAC2 Q92769 1/20 0.57
ALDH1A1 P00352 1/20 0.51
MAPT P10636 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9786700 0.95 MMP3 (0.61) MMP2MMP3HRH3HRH2HRH1
SCHEMBL1618099 0.94 ALDH1A1 (0.56) MMP2MMP3HRH3HRH2HRH1
SCHEMBL5091513 0.93 HDAC1 (0.62) MMP2MMP3HRH3HRH2HRH1
SCHEMBL5097477 0.93 HDAC1 (0.62) MMP2MMP3HRH3HRH2HRH1
SCHEMBL5097462 0.93 HDAC1 (0.62) MMP2MMP3HRH3HRH2HRH1
SCHEMBL9169148 0.93 HDAC1 (0.62) MMP2MMP3HRH3HRH2HRH1
SCHEMBL5097481 0.93 HDAC1 (0.62) MMP2MMP3HRH3HRH2HRH1
SCHEMBL4594927 0.93 HDAC1 (0.62) MMP2MMP3HRH3HRH2HRH1
SCHEMBL5091525 0.93 HDAC1 (0.62) MMP2MMP3HRH3HRH2HRH1
SCHEMBL5090877 0.93 HDAC1 (0.62) MMP2MMP3HRH3HRH2HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61047455-A None JP disclosed
EP-2562155-B1 HYDROXAMIC ACID DERIVATIVE TAISHO PHARMACEUTICAL CO LTD (JP) 2019-06-05 EP disclosed
EP-2562155-B1 HYDROXAMIC ACID DERIVATIVE TAISHO PHARMACEUTICAL CO LTD (JP) 2019-06-05 EP disclosed
US-9499477-B2 Hydroxamic acid derivative TOYAMA CHEMICAL CO., LTD. (JP) 2016-11-22 US disclosed
US-9499477-B2 Hydroxamic acid derivative TOYAMA CHEMICAL CO., LTD. (JP) 2016-11-22 US disclosed
US-9499477-B2 Hydroxamic acid derivative TOYAMA CHEMICAL CO., LTD. (JP) 2016-11-22 US disclosed
US-20150225335-A1 NOVEL HYDROXAMIC ACID DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD. (JP) 2015-08-13 US disclosed
US-20150225335-A1 NOVEL HYDROXAMIC ACID DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD. (JP) 2015-08-13 US disclosed
US-20150225335-A1 NOVEL HYDROXAMIC ACID DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD. (JP) 2015-08-13 US disclosed
US-9073821-B2 Hydroxamic acid derivative TAISHO PHARMACEUTICAL CO., LTD (JP) 2015-07-07 US disclosed
US-6180028-B1 ACRYLATED ESTERS ASAHI GLASS COMPANY LTD. (JP) 2001-01-30 US disclosed
EP-0955348-A1 LIQUID-CRYSTAL COMPOSITION AND POLYMERIC LIQUID CRYSTAL OBTAINED BY POLYMERIZING THE SAME Asahi Glass Company Ltd. (JP) 1999-11-10 EP disclosed
EP-0679633-B1 Diaminobenzene derivatives and polyimides prepared therefrom NISSAN CHEMICAL IND LTD (JP) 1999-11-03 EP disclosed
US-5861534-A CHEMICAL INTERMEDIATES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1999-01-19 US disclosed
US-5665856-A Diaminobenzene derivatives and polyimides prepared therefrom NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1997-09-09 US disclosed
EP-0679633-A1 Diaminobenzene derivatives and polyimides prepared therefrom NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1995-11-02 EP disclosed
EP-0171794-B1 ALCOHOL DERIVATIVES AND LIQUID CRYSTAL COMPOSITION CONTAINING THEM Chisso Corporation (JP) 1988-06-22 EP disclosed
US-4654162-A Alcohol derivatives CHISSO CORPORATION (JP) 1987-03-31 US disclosed
JP-S6147455-A 4-CYANO-4'-(HYDROXYALKOXY)BIPHENYL CHISSO CORP 1986-03-07 JP disclosed
EP-0171794-A1 Alcohol derivatives and liquid crystal composition containing them Chisso Corporation (JP) 1986-02-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150225335-A1 NOVEL HYDROXAMIC ACID DERIVATIVE LCT, AGXT, HDAC9 MMP2 111/4885MMP3 194/4885HRH3 1334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.