Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6443558 | 0.81 | PABPC1 (0.46) | HSD17B10NR4A1KDM5AMEN1KMT2A | |
| SCHEMBL501876 | 0.80 | ALDH1A1 (0.57) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29413047 | 0.80 | ALDH1A1 (0.57) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5543487 | 0.79 | PBRM1 (0.46) | HSD17B10KDM5AMEN1KMT2AKDM4E | |
| SCHEMBL4297093 | 0.79 | ALDH1A1 (0.51) | HSD17B10KDM5AMEN1KMT2AKDM4E | |
| SCHEMBL28172203 | 0.77 | NPC1 (0.56) | HSD17B10MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL534334 | 0.77 | G6PD (0.52) | HSD17B10KDM5AMEN1KMT2AKDM4E | |
| SCHEMBL29404347 | 0.77 | HSD17B10 (0.78) | HSD17B10NR4A1NR4A2NR4A3MEN1 | |
| Benzene SCHEMBL28110156 | 0.77 | HSD17B10 (0.78) | HSD17B10NR4A1NR4A2NR4A3MEN1 | |
| SCHEMBL7624693 | 0.77 | HSD17B10 (0.78) | HSD17B10NR4A1NR4A2NR4A3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020142334-A1 | Methods of detecting poly(ADP-ribose) polymerase enzymatic activity | BROWN JANICE A (US) | 2002-10-03 | — | — | US | disclosed |
| EP-1227322-A1 | Methods of detecting poly(ADP-ribose) polymerase enzymatic activity | Pfizer Products Inc. (US) | 2002-07-31 | — | — | EP | disclosed |