Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056140 | 0.92 | LMNA (0.46) | LMNAALDH1A1HSD17B10SMN1; SMN2ABCB1 | |
| SCHEMBL7589719 | 0.91 | LMNA (0.44) | LMNASMN1; SMN2ABCB1 | |
| SCHEMBL7594756 | 0.90 | LMNA (0.36) | LMNAABCB1 | |
| SCHEMBL8380655 | 0.89 | LMNA (0.42) | LMNAALDH1A1SMN1; SMN2ABCB1 | |
| SCHEMBL28880451 | 0.88 | LMNA (0.43) | LMNAALDH1A1SMN1; SMN2ABCB1 | |
| SCHEMBL9317092 | 0.88 | LMNA (0.43) | LMNAALDH1A1SMN1; SMN2ABCB1 | |
| SCHEMBL7588430 | 0.87 | LMNA (0.34) | LMNAABCB1 | |
| SCHEMBL8375513 | 0.87 | LMNA (0.41) | LMNAALDH1A1SMN1; SMN2ABCB1 | |
| SCHEMBL9009307 | 0.87 | LMNA (0.43) | LMNAALDH1A1SMN1; SMN2ABCB1 | |
| SCHEMBL7600638 | 0.86 | ABCB1 (0.33) | LMNAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |
| US-6310243-B1 | BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY | NYCOMED IMAGING AS (NO) | 2001-10-30 | — | — | US | disclosed |
| WO-2000037115-A1 | WATER-SOLUBLE CONTRAST MEDIA FOR X-RAY IMAGING | NYCOMED IMAGING AS (NO) | 2000-06-29 | — | — | WO | disclosed |
| US-5993780-A | A POLYIODOARYLALKYL ALCOHOL OR DERIVATIVE | NYCOMED IMAGING AS (NO) | 1999-11-30 | — | — | US | disclosed |