SCHEMBL28880451

SCHEMBL28880451

CC(=O)OCC(=O)Nc1c(I)c(C(N)=O)c(I)c(C(=O)NCC(COC(C)=O)OC(C)=O)c1I

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.43
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
ABCB1 P08183 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7056140 0.96 LMNA (0.46) LMNACYP2C19HIF1AABCB1SMN1; SMN2
SCHEMBL8375513 0.93 LMNA (0.41) LMNACYP2C19HIF1AABCB1SMN1; SMN2
SCHEMBL9317092 0.92 LMNA (0.43) LMNACYP2C19HIF1AABCB1SMN1; SMN2
SCHEMBL9009307 0.91 LMNA (0.43) LMNACYP2C19HIF1AABCB1SMN1; SMN2
SCHEMBL8380655 0.90 LMNA (0.42) LMNACYP2C19HIF1AABCB1SMN1; SMN2
SCHEMBL8905997 0.90 LMNA (0.38) LMNACYP2C19HIF1AABCB1SMN1; SMN2
SCHEMBL3384375 0.89 LMNA (0.54) LMNACYP2C19HIF1AABCB1ALDH1A1
SCHEMBL8377994 0.88 LMNA (0.38) LMNACYP2C19HIF1AABCB1
SCHEMBL7590487 0.88 LMNA (0.40) LMNAABCB1SMN1; SMN2ALDH1A1
SCHEMBL12871782 0.87 LMNA (0.41) LMNACYP2C19HIF1AABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115160174-A Synthesis method of ioversol 浙江海洲制药有限公司 2022-10-11 CN claimed
CN-115160174-A Synthesis method of ioversol 浙江海洲制药有限公司 2022-10-11 CN disclosed