Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056140 | 0.96 | LMNA (0.46) | LMNACYP2C19HIF1AABCB1ALDH1A1 | |
| SCHEMBL28880451 | 0.92 | LMNA (0.43) | LMNACYP2C19HIF1AABCB1ALDH1A1 | |
| SCHEMBL9009307 | 0.91 | LMNA (0.43) | LMNACYP2C19HIF1AABCB1ALDH1A1 | |
| SCHEMBL8380655 | 0.90 | LMNA (0.42) | LMNACYP2C19HIF1AABCB1ALDH1A1 | |
| SCHEMBL3384375 | 0.89 | LMNA (0.54) | LMNACYP2C19HIF1AABCB1ALDH1A1 | |
| SCHEMBL8375513 | 0.88 | LMNA (0.41) | LMNACYP2C19HIF1AABCB1ALDH1A1 | |
| SCHEMBL7590487 | 0.88 | LMNA (0.40) | LMNAABCB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12871782 | 0.87 | LMNA (0.41) | LMNACYP2C19HIF1AABCB1 | |
| SCHEMBL8375493 | 0.86 | LMNA (0.41) | LMNACYP2C19HIF1AABCB1ALDH1A1 | |
| SCHEMBL9009229 | 0.85 | LMNA (0.51) | LMNACYP2C19HIF1AABCB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356613-A | X-ray contrast agents, compositions and methods | MALLINCKRODT MEDICAL, INC. (US) | 1994-10-18 | — | — | US | disclosed |
| US-5019371-A | Novel x-ray contrast agents, compositions and methods | MALLINCKRODT MEDICAL, INC. (US) | 1991-05-28 | — | — | US | disclosed |