Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 15/20 | 0.59 |
| ▸ | ITGB6 | P18564 | 6/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | ITGB8 | P26012 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7589535 | 1.00 | ITGAV (0.59) | ITGAVITGB3ITGB6ITGB1ITGA2B | |
| SCHEMBL7552205 | 0.83 | ITGAV (0.41) | ITGAVITGB3ITGB6ITGB8 | |
| SCHEMBL4374753 | 0.81 | ITGB3 (0.65) | ITGAVITGB3ITGB6ITGB1ITGA2B | |
| SCHEMBL4379967 | 0.81 | ITGB3 (0.65) | ITGAVITGB3ITGB6ITGB1ITGA2B | |
| SCHEMBL7595642 | 0.80 | ITGAV (0.63) | ITGAVITGB3ITGB6ITGB1ITGA2B | |
| SCHEMBL7553084 | 0.80 | ITGAV (0.63) | ITGAVITGB3ITGB6ITGB1ITGA2B | |
| SCHEMBL7592559 | 0.80 | ITGAV (0.63) | ITGAVITGB3ITGB6ITGB1ITGA2B | |
| SCHEMBL7592208 | 0.78 | ITGAV (0.45) | ITGAVITGB3ITGB6ITGA2BITGB8 | |
| SCHEMBL7590655 | 0.78 | ITGAV (0.45) | ITGAVITGB3ITGB6ITGA2BITGB8 | |
| SCHEMBL7552889 | 0.78 | ITGAV (0.45) | ITGAVITGB3ITGB6ITGA2BITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1040098-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (a New Jersey corp.) (US) | 2000-10-04 | — | — | EP | disclosed |
| WO-1999031061-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |