SCHEMBL7590699

SCHEMBL7590699

CCCC(Br)CCC(=O)OCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.47
ALDH1A1 P00352 3/20 0.45
TRPA1 O75762 1/20 0.45
KMT2A Q03164 2/20 0.45
POLB P06746 2/20 0.45
CYP1A2 P05177 1/20 0.44
GAA P10253 2/20 0.43
MGAM O43451 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
TSHR P16473 2/20 0.41
CYP3A4 P08684 1/20 0.41
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP4F2 P78329 3/20 0.39
CYP4A11 Q02928 3/20 0.39
NR1I2 O75469 1/20 0.36
PGR P06401 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
PTGS2 P35354 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7522785 0.86 L3MBTL1 (0.49) L3MBTL1ALDH1A1TRPA1KMT2APOLB
SCHEMBL6584152 0.84 L3MBTL1 (0.47) L3MBTL1ALDH1A1TRPA1KMT2APOLB
SCHEMBL852674 0.82 ALDH1A1 (0.46) L3MBTL1ALDH1A1TRPA1KMT2APOLB
SCHEMBL11371695 0.82 TSHR (0.48) L3MBTL1ALDH1A1KMT2APOLBGAA
SCHEMBL25411536 0.81 L3MBTL1 (0.52) L3MBTL1ALDH1A1TRPA1KMT2APOLB
SCHEMBL1206813 0.79 L3MBTL1 (0.50) L3MBTL1ALDH1A1TRPA1KMT2APOLB
SCHEMBL20398910 0.78 TSHR (0.56) ALDH1A1KMT2ACYP1A2TSHRCYP3A4
SCHEMBL6067665 0.78 L3MBTL1 (0.49) L3MBTL1ALDH1A1TRPA1KMT2APOLB
SCHEMBL2222305 0.78 L3MBTL1 (0.53) L3MBTL1ALDH1A1TRPA1KMT2APOLB
SCHEMBL25186835 0.78 L3MBTL1 (0.49) L3MBTL1ALDH1A1TRPA1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1255758-A1 APOPTOSIS-INDUCING COMPOUNDS THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) 2002-11-13 EP disclosed
WO-2001058904-A9 APOPTOSIS-INDUCING COMPOUNDS TRINITY COLLEGE DUBLIN (IE) 2002-02-21 WO disclosed
WO-2001058904-A1 APOPTOSIS-INDUCING COMPOUNDS THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) 2001-08-16 WO disclosed
US-4254262-A IN THE PRESENCE OF A QUATERNARY AMMONIUM OR PHOSPHONIUM SALT IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1981-03-03 US disclosed