SCHEMBL2222305

SCHEMBL2222305

CCOC(=O)CCC(Br)C(=O)OCC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.53
KMT2A Q03164 2/20 0.50
POLB P06746 2/20 0.50
ALDH1A1 P00352 6/20 0.46
TRPA1 O75762 1/20 0.46
CYP1A2 P05177 1/20 0.45
GAA P10253 2/20 0.44
MGAM O43451 1/20 0.44
SI P14410 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44
ZDHHC7 Q9NXF8 1/20 0.40
TSHR P16473 3/20 0.38
CYP4F2 P78329 2/20 0.38
CYP4A11 Q02928 2/20 0.38
CYP3A4 P08684 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
ATM Q13315 1/20 0.38
NR1I2 O75469 1/20 0.37
PGR P06401 1/20 0.37
ADORA3 P0DMS8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21262163 0.88 CYP1A2 (0.52) L3MBTL1KMT2APOLBALDH1A1TRPA1
SCHEMBL28865583 0.88 L3MBTL1 (0.42) L3MBTL1KMT2APOLBALDH1A1TRPA1
SCHEMBL1674842 0.88 CYP1A2 (0.52) L3MBTL1KMT2APOLBALDH1A1TRPA1
SCHEMBL27750312 0.86 KMT2A (0.50) L3MBTL1KMT2APOLBALDH1A1TRPA1
SCHEMBL27278231 0.86 L3MBTL1 (0.47) L3MBTL1KMT2APOLBALDH1A1TRPA1
SCHEMBL9714798 0.85 ZDHHC7 (0.51) L3MBTL1KMT2APOLBALDH1A1TRPA1
SCHEMBL9489696 0.85 ZDHHC7 (0.51) L3MBTL1KMT2APOLBALDH1A1TRPA1
SCHEMBL240521 0.84 ZDHHC7 (0.47) L3MBTL1KMT2APOLBALDH1A1TRPA1
SCHEMBL36999 0.84 ZDHHC7 (0.47) L3MBTL1KMT2APOLBALDH1A1TRPA1
SCHEMBL20321136 0.84 L3MBTL1 (0.46) L3MBTL1KMT2APOLBALDH1A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250270235-A1 COMPLEX OF GADOLINIUM AND A CHELATING LIGAND DERIVED OF A DIASTEREOISOMERICALLY ENRICHED PCTA AND SYNTHESIS METHOD GUERBET SA (FR) 2025-08-28 US disclosed
CN-119552163-A Complexes of gadolinium and chelating ligands based on diastereoisomerically enriched PCTA and methods of making and purifying same 法国加栢 2025-03-04 CN disclosed
CN-113698400-B Diastereoisomeric enriched complexes of gadolinium and PCTA-based chelating ligands and methods of synthesis 法国加栢 2025-01-28 CN disclosed
CN-113646308-B Complexes of gadolinium and chelating ligands based on diastereoisomerically enriched PCTA and methods of making and purifying same 法国加栢 2024-12-13 CN disclosed
CN-113646309-B Diastereoisomeric enriched complexes of gadolinium and PCTA-based chelating ligands and methods of synthesis 法国加栢 2024-11-22 CN disclosed
CN-118791488-B Compounds, chelates and their use in magnetic resonance imaging 成都施贝康生物医药科技有限公司 2024-11-15 CN disclosed
US-20240358863-A1 COMPLEX OF GADOLINIUM AND A CHELATING LIGAND DERIVED FROM A DIASTEREOISOMERICALLY ENRICHED PCTA AND PREPARATION AND PURIFICATION PROCESS GUERBET SA (FR) 2024-10-31 US disclosed
CN-118791488-A Compounds, chelates and their use in magnetic resonance imaging 成都施贝康生物医药科技有限公司 2024-10-18 CN disclosed
US-12064487-B2 Complex of gadolinium and a chelating ligand derived from a diastereoisomerically enriched PCTA and preparation and purification process GUERBET (FR) 2024-08-20 US disclosed
US-12036289-B2 Gadolinium bearing PCTA-based contrast agents BRACCO IMAGING S.P.A. (IT) 2024-07-16 US disclosed
US-5034418-A Anticoagulants EISAI CO., LTD. (JP) 1991-07-23 US disclosed
US-4978767-A ANTICOAGULANTS EISAI CO., LTD. (JP) 1990-12-18 US disclosed
US-4954523-A ANTICOAGULANT EISAI CO., LTD. (JP) 1990-09-04 US disclosed
US-4920131-A Quinoline derivatives and use thereof as antagonists of leukotriene D4 RORER PHARMACEUTICAL CORP. (US) 1990-04-24 US disclosed
US-4918081-A Quinoline derivatives and use thereof as antagonists of leukotriene d4 RORER PHARMACEUTICAL CORP. (US) 1990-04-17 US disclosed
WO-1989012628-A1 QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 RORER INTERNATIONAL (OVERSEAS) INC. (US) 1989-12-28 WO disclosed
WO-1989012629-A1 QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 RORER INTERNATIONAL (OVERSEAS) INC. (US) 1989-12-28 WO disclosed
EP-0348155-A1 Quinoline derivatives as antagonists of leukotriene D4, compositions containing the same and processes for their preparation RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1989-12-27 EP disclosed
US-4886834-A ANTICOAGULANTS EISAI CO., LTD. (JP) 1989-12-12 US disclosed
EP-0238973-A2 Diphenyl-methane derivative, pharmaceutical composition and use Eisai Co., Ltd. (JP) 1987-09-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250270235-A1 COMPLEX OF GADOLINIUM AND A CHELATING LIGAND DERIVED OF A DIASTEREOISOMERICALLY ENRICHED PCTA AND SYNTHESIS METHOD CCKBR, SCLY, GRPR L3MBTL1 4202/4885KMT2A 2183/4885POLB 2737/4885
US-20240358863-A1 COMPLEX OF GADOLINIUM AND A CHELATING LIGAND DERIVED FROM A DIASTEREOISOMERICALLY ENRICHED PCTA AND PREPARATION AND PURIFICATION PROCESS TSHR, QRFPR, SCTR L3MBTL1 4325/4885KMT2A 2441/4885POLB 3094/4885
US-12064487-B2 Complex of gadolinium and a chelating ligand derived from a diastereoisomerically enriched PCTA and preparation and purification process TSHR, QRFPR, SCTR L3MBTL1 4325/4885KMT2A 2441/4885POLB 3094/4885
US-12036289-B2 Gadolinium bearing PCTA-based contrast agents GLRX3, GLRA1, GRHPR L3MBTL1 2820/4885KMT2A 2230/4885POLB 3869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.