Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.42 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7587566 | 0.90 | P2RX7 (0.52) | POLBP2RX7LMNAMEN1KMT2A | |
| SCHEMBL7582641 | 0.77 | POLB (0.41) | POLBMEN1KMT2AHTT | |
| SCHEMBL17040326 | 0.72 | P2RX7 (0.52) | P2RX7NR1H2NR1H3PHGDHSIGMAR1 | |
| SCHEMBL7585368 | 0.71 | POLB (0.39) | POLB | |
| SCHEMBL7594794 | 0.71 | ALDH1A1 (0.40) | — | |
| SCHEMBL17037456 | 0.71 | P2RX7 (0.50) | P2RX7NR1H2NR1H3PHGDHSIGMAR1 | |
| SCHEMBL15055274 | 0.70 | CHRM1 (0.54) | LMNAKMT2A | |
| SCHEMBL15055273 | 0.70 | CHRM1 (0.54) | LMNAKMT2A | |
| SCHEMBL27430288 | 0.70 | P2RX7 (0.39) | P2RX7NR1H2NR1H3 | |
| SCHEMBL3029177 | 0.68 | CA1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675118-B1 | Biphenylderivatives, process for their preparation and their use as medicaments | EISAI CO LTD (JP) | 2002-10-09 | — | — | EP | claimed |