Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154882 | 0.84 | CES2 (0.52) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL7154879 | 0.84 | CES2 (0.52) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL1268926 | 0.79 | CES2 (0.48) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL372685 | 0.79 | CES2 (0.48) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL6058330 | 0.79 | CES2 (0.48) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL4788436 | 0.78 | FNTA (0.62) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL10478367 | 0.78 | FNTA (0.62) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL4331635 | 0.78 | FNTA (0.62) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL19144233 | 0.77 | CES1 (0.46) | GPR84PPARGPPARDPPARAHDAC11 | |
| Bicarbonate SCHEMBL21110933 | 0.76 | GPR84 (0.56) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131273-A1 | 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2001-09-12 | — | — | EP | claimed |
| WO-2000029362-A1 | 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2000-05-25 | — | — | WO | claimed |
| EP-1202948-A1 | PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-05-08 | — | — | EP | disclosed |
| EP-1131273-A1 | 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2001-09-12 | — | — | EP | disclosed |
| WO-2001012578-A1 | PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-22 | — | — | WO | disclosed |
| WO-2000029362-A1 | 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2000-05-25 | — | — | WO | disclosed |