SCHEMBL7591600

SCHEMBL7591600

CCCC1OC(=O)CC1(O)O

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.36
KAT2A Q92830 3/20 0.34
LMNA P02545 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP1A2 P05177 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27946496 0.78 PRKCA (0.31) PRKCA
SCHEMBL17297568 0.73 PRKCA (0.31) PRKCACYP1A2
SCHEMBL13813543 0.69 LMNA (0.38) PRKCAKAT2ALMNACYP2C9CYP1A2
SCHEMBL17300291 0.67 CYP3A4 (0.32)
SCHEMBL14715934 0.67 CYP1A2 (0.49) PRKCACYP1A2
SCHEMBL17300296 0.66 PRKCA (0.30) PRKCA
SCHEMBL16150048 0.65 PRKCA (0.33) PRKCA
SCHEMBL17836049 0.64 KAT2A (0.33) PRKCAKAT2ACYP1A2
SCHEMBL7591699 0.64 LMNA (0.31) LMNACYP2C9
SCHEMBL5796626 0.64 PRKCA (0.33) PRKCALMNACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1246811-A1 METHODS FOR RESOLVING RACEMIC MIXTURES OF 5-SUBSTITUTED 4-HYDROXY-2-FURANONES OXIS Isle of Man, Limited (GB) 2002-10-09 EP disclosed
WO-2001049671-A1 METHODS FOR RESOLVING RACEMIC MIXTURES OF 5-SUBSTITUTED 4-HYDROXY-2-FURANONES OXIS ISLE OF MAN, LIMITED (US) 2001-07-12 WO disclosed