Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17300318 | 0.65 | HMGCR (0.32) | — | |
| SCHEMBL7591600 | 0.64 | PRKCA (0.36) | LMNACYP2C9 | |
| SCHEMBL19229720 | 0.63 | — | — | |
| SCHEMBL10883048 | 0.62 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL22950788 | 0.60 | AKR1B1 (0.44) | — | |
| SCHEMBL1106721 | 0.59 | SMN1; SMN2 (0.40) | SMN1; SMN2 | |
| SCHEMBL6256448 | 0.59 | CA2 (0.38) | LMNACYP2C9SMN1; SMN2 | |
| SCHEMBL11649177 | 0.58 | SMN1; SMN2 (0.44) | LMNACYP2C9SMN1; SMN2 | |
| SCHEMBL6263831 | 0.58 | LMNA (0.44) | LMNACYP2C9SMN1; SMN2 | |
| SCHEMBL24840437 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246811-A1 | METHODS FOR RESOLVING RACEMIC MIXTURES OF 5-SUBSTITUTED 4-HYDROXY-2-FURANONES | OXIS Isle of Man, Limited (GB) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001049671-A1 | METHODS FOR RESOLVING RACEMIC MIXTURES OF 5-SUBSTITUTED 4-HYDROXY-2-FURANONES | OXIS ISLE OF MAN, LIMITED (US) | 2001-07-12 | — | — | WO | disclosed |