Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | JUN | P05412 | 1/20 | 0.58 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | GUSB | P08236 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2936063 | 0.84 | NFKB1 (0.71) | NFKB1CA1CA2CA4JUN | |
| SCHEMBL2936064 | 0.84 | NFKB1 (0.71) | NFKB1CA1CA2CA4JUN | |
| SCHEMBL2936065 | 0.84 | NFKB1 (0.71) | NFKB1CA1CA2CA4JUN | |
| SCHEMBL7607193 | 0.84 | NFKB1 (0.53) | NFKB1CA1CA2CA4JUN | |
| SCHEMBL7583112 | 0.79 | PTPN1 (0.42) | NFKB1CA1CA2CA4JUN | |
| SCHEMBL27781270 | 0.78 | NFKB1 (0.70) | NFKB1CA1CA2CA4JUN | |
| O-Coumaric Acid SCHEMBL29353381 | 0.76 | NFKB1 (1.00) | NFKB1CA1CA2CA4JUN | |
| O-Coumaric Acid SCHEMBL892006 | 0.76 | NFKB1 (1.00) | NFKB1CA1CA2CA4JUN | |
| O-Coumaric Acid SCHEMBL29368085 | 0.76 | NFKB1 (1.00) | NFKB1CA1CA2CA4JUN | |
| O-Coumaric Acid SCHEMBL64885 | 0.76 | NFKB1 (1.00) | NFKB1CA1CA2CA4JUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060574-A1 | ALPHA BETA MODULATING PEPTIDES | Alzhyme Pty Ltd (AU) | 2016-08-31 | — | — | EP | disclosed |
| WO-2015058258-A1 | AΒ MODULATING PEPTIDES | ALZHYME PTY LTD (AU) | 2015-04-30 | — | — | WO | disclosed |
| EP-1263454-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | Praecis Pharmaceuticals Incorporated (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2000052048-A9 | MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARM INC (US) | 2002-04-11 | — | — | WO | disclosed |
| EP-1161449-A1 | MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | Praecis Pharmaceuticals Incorporated (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2001058470-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2001-08-16 | — | — | WO | disclosed |
| WO-2000052048-A1 | MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2000-09-08 | — | — | WO | disclosed |