SCHEMBL7607193

SCHEMBL7607193

O=C(O)C(=Cc1ccccc1O)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA4 P22748 2/20 0.53
TRIM24 O15164 1/20 0.52
TRIM33 Q9UPN9 1/20 0.52
JUN P05412 1/20 0.50
NFE2L2 Q16236 1/20 0.50
TP53 P04637 1/20 0.48
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
TRPA1 O75762 1/20 0.47
CDK4 P11802 1/20 0.45
CCND1 P24385 1/20 0.45
CTRC Q99895 1/20 0.44
DUSP3 P51452 1/20 0.44
PTPN5 P54829 1/20 0.44
PTPN11 Q06124 1/20 0.44
BCHE P06276 1/20 0.44
GUSB P08236 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16287426 0.86 TP53 (0.56) NFKB1CA1CA2CA4TP53
SCHEMBL7591687 0.84 NFKB1 (0.61) NFKB1CA1CA2CA4JUN
SCHEMBL8669956 0.83 ERN1 (0.55) NFKB1CA1CA2CA4TP53
SCHEMBL4452379 0.83 CA2 (0.53) NFKB1CA1CA2CA4TRIM24
SCHEMBL4924447 0.81 MAPT (0.55) NFKB1CA1CA2CA4TRIM24
SCHEMBL7067852 0.79 CA2 (0.50) NFKB1CA1CA2CA4TRIM24
SCHEMBL208434 0.79 AKR1C3 (0.59) NFKB1CA1CA2CA4TRIM24
SCHEMBL9132013 0.79 NFKB1 (0.50) NFKB1CA1CA2CA4TRIM24
SCHEMBL9132020 0.79 NFKB1 (0.50) NFKB1CA1CA2CA4TRIM24
SCHEMBL1137305 0.79 AKR1C3 (0.59) NFKB1CA1CA2CA4TRIM24

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110396869-B Process method for improving strength failure period of cardboard paper 山鹰国际控股股份公司 2021-07-27 CN claimed
CN-110396869-A A kind of process improving boxboard intensity failure period SHANYING INT HOLDINGS CO LTD 2019-11-01 CN claimed
US-20020016488-A1 UV-PHOTOPROTECTIVE DIBENZOYLMETHANE COMPOSITIONS COMPRISING PHOTOSTABILIZING AMOUNTS OF BENZALMALONATE SILANES FORESTIER SERGE (FR) 2002-02-07 US claimed
EP-0868905-A2 Method for enhancing the photostability of a dibenzoylmethane derivate with a silane benzalmalonate and method of preparation of silane bezalmalonates L'OREAL (FR) 1998-10-07 EP claimed
CN-110396869-B Process method for improving strength failure period of cardboard paper 山鹰国际控股股份公司 2021-07-27 CN disclosed
CN-110396869-A A kind of process improving boxboard intensity failure period SHANYING INT HOLDINGS CO LTD 2019-11-01 CN disclosed
US-6426428-B2 SUNSCREENS/COSMETICS USED ON HUMAN HAIR AND/OR SKING Societe L′Oreal (FR) 2002-07-30 US disclosed
US-20020016488-A1 UV-PHOTOPROTECTIVE DIBENZOYLMETHANE COMPOSITIONS COMPRISING PHOTOSTABILIZING AMOUNTS OF BENZALMALONATE SILANES FORESTIER SERGE (FR) 2002-02-07 US disclosed
US-5951968-A UV-photoprotective dibenzoylmethane compositions comprising photostabilizing amounts of benzalmalonate silanes SOCIETE L'OREAL S.A. (FR) 1999-09-14 US disclosed
EP-0868905-A2 Method for enhancing the photostability of a dibenzoylmethane derivate with a silane benzalmalonate and method of preparation of silane bezalmalonates L'OREAL (FR) 1998-10-07 EP disclosed
US-3943094-A Polymers and copolymers based on alkenoyl-oxybenzylidene-malonic esters as UV-absorbers and polymers stabilized therewith BAYER AKTIENGESELLSCHAFT (DT) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020016488-A1 UV-PHOTOPROTECTIVE DIBENZOYLMETHANE COMPOSITIONS COMPRISING PHOTOSTABILIZING AMOUNTS OF BENZALMALONATE SILANES TST, TMT1A, TBCA NFKB1 926/4885CA1 3323/4885CA2 2972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.