Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGFBP3 | P17936 | 11/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | IGFBP1 | P08833 | 1/20 | 0.42 |
| ▸ | IGFBP2 | P18065 | 1/20 | 0.42 |
| ▸ | IGFBP4 | P22692 | 1/20 | 0.42 |
| ▸ | IGFBP6 | P24592 | 1/20 | 0.42 |
| ▸ | IGFBP5 | P24593 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9327979 | 0.81 | IGFBP3 (0.52) | IGFBP3IGFBP1IGFBP2IGFBP4IGFBP6 | |
| SCHEMBL155043 | 0.81 | EGLN1 (0.54) | EGLN1KMT2AGABRPGABRDGABRA1 | |
| SCHEMBL29489052 | 0.81 | EGLN1 (0.54) | EGLN1KMT2AGABRPGABRDGABRA1 | |
| SCHEMBL29746814 | 0.81 | EGLN1 (0.54) | EGLN1KMT2AGABRPGABRDGABRA1 | |
| SCHEMBL3205661 | 0.80 | IGFBP3 (0.49) | IGFBP3IGFBP1IGFBP2IGFBP4IGFBP6 | |
| SCHEMBL27360353 | 0.79 | EGLN1 (0.53) | EGLN1KMT2AGABRPGABRDGABRA1 | |
| Hydrochloric Acid SCHEMBL27469719 | 0.79 | EGLN1 (0.53) | EGLN1KMT2AGABRPGABRDGABRA1 | |
| Water SCHEMBL1201320 | 0.79 | EGLN1 (0.53) | EGLN1KMT2AGABRPGABRDGABRA1 | |
| Methyl Alcohol SCHEMBL28240452 | 0.77 | EGLN1 (0.51) | EGLN1KMT2AGABRPGABRDGABRA1 | |
| Hydrochloric Acid SCHEMBL28181942 | 0.77 | EGLN1 (0.51) | EGLN1KMT2AGABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263454-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | Praecis Pharmaceuticals Incorporated (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2000052048-A9 | MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARM INC (US) | 2002-04-11 | — | — | WO | disclosed |
| EP-1161449-A1 | MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | Praecis Pharmaceuticals Incorporated (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2001058470-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2001-08-16 | — | — | WO | disclosed |
| WO-2000052048-A1 | MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2000-09-08 | — | — | WO | disclosed |
| EP-0929574-A1 | MODULATORS OF beta-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | Praecis Pharmaceuticals Incorporated (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998008868-A9 | MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | — | 1998-05-28 | — | — | WO | disclosed |
| WO-1998008868-A1 | MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 1998-03-05 | — | — | WO | disclosed |