SCHEMBL9327979

SCHEMBL9327979

O=C(O)c1cc2ccccc2c(C(=O)O)n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IGFBP3 P17936 6/20 0.52
KDM4E B2RXH2 3/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
ALDH1A1 P00352 2/20 0.52
CYP1A2 P05177 1/20 0.52
GLA P06280 1/20 0.52
HPGD P15428 1/20 0.52
CYP2C19 P33261 1/20 0.52
HSD17B10 Q99714 1/20 0.52
ALOX15 P16050 3/20 0.47
MAPT P10636 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MGAM O43451 1/20 0.44
TSHR P16473 2/20 0.43
ACMSD Q8TDX5 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
IGFBP1 P08833 1/20 0.43
IGFBP2 P18065 1/20 0.43
IGFBP4 P22692 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3205661 0.87 IGFBP3 (0.49) IGFBP3KDM4EMEN1KMT2AALDH1A1
SCHEMBL310340 0.86 IGFBP3 (0.48) IGFBP3KDM4EMEN1KMT2AALDH1A1
SCHEMBL4768998 0.81 KDM4E (0.52) IGFBP3KDM4EMEN1KMT2AALDH1A1
SCHEMBL29079315 0.81 MEN1 (0.52) KDM4EMEN1KMT2AALDH1A1CYP1A2
SCHEMBL7591756 0.81 IGFBP3 (0.50) IGFBP3KDM4EMEN1KMT2AALDH1A1
SCHEMBL7591735 0.81 CNR2 (0.50) IGFBP3KDM4EMEN1KMT2AALDH1A1
SCHEMBL754048 0.79 MEN1 (0.50) KDM4EMEN1KMT2AALDH1A1CYP1A2
SCHEMBL755479 0.79 MEN1 (0.50) KDM4EMEN1KMT2AALDH1A1CYP1A2
SCHEMBL1202533 0.79 ALDH1A1 (0.50) IGFBP3KDM4EMEN1KMT2AALDH1A1
SCHEMBL6981683 0.79 KDM4E (0.50) IGFBP3KDM4EMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0377357-B1 Process for the condensation of at least one epoxide on at least one cyclic anhyhride in the presence of a titanium-based catalyst INST FRANCAIS DU PETROLE (FR) 1994-03-23 EP claimed
US-4997910-A Polyesters INSTITUT FRANCAIS DU PETROLE (FR) 1991-03-05 US claimed
CN-112978709-A Carbon quantum dot precursor composition, carbon quantum dot and preparation method thereof 中国科学院大连化学物理研究所 2021-06-18 CN disclosed
US-4997910-A Polyesters INSTITUT FRANCAIS DU PETROLE (FR) 1991-03-05 US disclosed
US-4255597-A FROM PARTIALLY CHLORINATED CYCLOPENTADIENE IN LIQUID PHASE, PHENANTHROLINE OR 8-HYDROXYQUINOLINE TO REDUCE COKING VELSICOL CHEMICAL CORPORATION (US) 1981-03-10 US disclosed