Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trolamine SCHEMBL434089 | 0.82 | MAPT (0.47) | MAPTKDM4EALOX15SMN1; SMN2CYP1A2 | |
| Trolamine SCHEMBL4748243 | 0.82 | MAPT (0.47) | MAPTKDM4EALOX15SMN1; SMN2CYP1A2 | |
| Trolamine SCHEMBL1146 | 0.82 | MAPT (0.47) | MAPTKDM4EALOX15SMN1; SMN2CYP1A2 | |
| Trolamine SCHEMBL15845959 | 0.82 | MAPT (0.47) | MAPTKDM4EALOX15SMN1; SMN2CYP1A2 | |
| Trolamine SCHEMBL8142068 | 0.79 | MAPT (0.42) | MAPTKDM4EALOX15SMN1; SMN2CYP1A2 | |
| SCHEMBL23528233 | 0.78 | MAPT (0.46) | MAPTKDM4EALOX15SMN1; SMN2CYP1A2 | |
| Trolamine SCHEMBL5934922 | 0.78 | MAPT (0.44) | MAPTKDM4EALOX15SMN1; SMN2CYP1A2 | |
| Trolamine SCHEMBL2051249 | 0.78 | MAPT (0.44) | MAPTKDM4EALOX15SMN1; SMN2CYP1A2 | |
| Trolamine SCHEMBL565435 | 0.78 | MAPT (0.44) | MAPTKDM4EALOX15SMN1; SMN2CYP1A2 | |
| Trolamine SCHEMBL9716114 | 0.78 | TSHR (0.46) | MAPTKDM4EALOX15SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922072-B1 | FLAME RETARDANT COMPOSITION | DU PONT (US) | 2002-10-23 | — | — | EP | disclosed |