Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 4/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1739174 | 0.90 | MDM4 (0.54) | MDM4TP53SLC17A5TLR2CASP3 | |
| SCHEMBL10020438 | 0.90 | MDM4 (0.54) | MDM4TP53SLC17A5TLR2CASP3 | |
| SCHEMBL31197005 | 0.84 | MDM4 (0.54) | MDM4TP53SLC17A5TLR2CASP3 | |
| SCHEMBL13253077 | 0.83 | CASP3 (0.48) | MDM4TP53SLC17A5CASP3MDM2 | |
| SCHEMBL16288088 | 0.82 | PTPN1 (0.48) | MDM4TP53SLC17A5CASP3 | |
| SCHEMBL29540266 | 0.82 | PTPN1 (0.48) | MDM4TP53SLC17A5CASP3 | |
| SCHEMBL27222134 | 0.82 | PTPN1 (0.48) | MDM4TP53SLC17A5CASP3 | |
| SCHEMBL6517147 | 0.81 | CASP3 (0.47) | MDM4TP53SLC17A5CASP3 | |
| SCHEMBL27129147 | 0.81 | MDM4 (0.49) | MDM4TP53SLC17A5CASP3MDM2 | |
| SCHEMBL27008576 | 0.81 | MDM4 (0.49) | MDM4TP53SLC17A5CASP3MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1207909-A2 | METHOD FOR COUPLING MOLECULES | MEDICAL RESEARCH COUNCIL (GB) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001015737-A2 | METHOD FOR COUPLING MOLECULES | MEDICAL RESEARCH COUNCIL (GB) | 2001-03-08 | — | — | WO | disclosed |