Triaziquone

Triaziquone

SCHEMBL759304

CC1(C)C(O)CCN(O)C1(C)C.O=C(O)CC(O)(CC(=O)O)C(=O)O.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2

The experimentally established mechanism targets of Triaziquone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL5307413 0.86
Triaziquone SCHEMBL7147458 0.82 ALDH1A1 (0.31)
Citric Acid SCHEMBL2293604 0.82 ALDH1A1 (0.43)
Triaziquone SCHEMBL2236656 0.82 ALDH1A1 (0.43)
Triaziquone SCHEMBL6236164 0.79 ALDH1A1 (0.36)
Edetic Acid SCHEMBL23361308 0.74 ALDH1A1 (0.35)
Triaziquone SCHEMBL22346328 0.69 DNMT1 (0.39)
Triaziquone SCHEMBL9361087 0.69 CA4 (0.38)
Triaziquone SCHEMBL22660873 0.67
Triaziquone SCHEMBL4299467 0.67 DNMT1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12257332-B2 Prevention of the oxidation of perfumery raw materials FIRMENICH SA (CH) 2025-03-25 US claimed
CN-119033623-A Guaiac azulene liposome and preparation method and application thereof 江门职业技术学院 2024-11-29 CN claimed
CN-118986777-A Nanometer liposome protective agent with ultraviolet resistance and oxidation resistance functions, preparation method, preparation and application thereof 江门职业技术学院 2024-11-22 CN claimed
CN-118215459-A Cosmetic composition comprising a mixture of isatin and an oxidizing agent 娇韵诗实验室 2024-06-18 CN claimed
CN-111655221-B Prevention of oxidation of perfume raw materials 弗门尼舍有限公司 2024-03-29 CN claimed
CN-115137657-B Composition for stabilizing color of cosmetic gardenia pigment and application thereof 上海百雀羚生物科技有限公司 2024-02-23 CN claimed
WO-2023245462-A1 STABILIZED COMPOSITION COMPRISING THIOPYRIDINONE COMPOUND L'OREAL (FR) 2023-12-28 WO claimed
CN-116600776-A Antioxidant composition 国际香精香料公司 2023-08-15 CN claimed
CN-115300417-A Sunscreen cream suitable for children and sensitive muscles and preparation method thereof 诺斯贝尔化妆品股份有限公司 2022-11-08 CN claimed
CN-110831569-B Photoprotective compositions 欧莱雅 2022-10-21 CN claimed
CN-111655221-A Prevention of oxidation of perfume raw materials 弗门尼舍有限公司 2020-09-11 CN claimed
CN-110831569-A Photoprotective composition comprising a dibenzoylmethane derivative, a merocyanine compound and a compound capable of accepting the energy of the triplet excitation level of the dibenzoylmethane compound 欧莱雅 2020-02-21 CN claimed
US-20190224094-A1 COLOR DEPOSITING SHAMPOO Celeb LLC (US) 2019-07-25 US claimed
US-10245221-B2 Stabilized color depositing shampoo Celeb LLC (US) 2019-04-02 US claimed
WO-2019036591-A1 STABILIZED COLOR DEPOSITING SHAMPOO Celeb LLC (US) 2019-02-21 WO claimed
US-20180168976-A1 STABILIZED COLOR DEPOSITING SHAMPOO Celeb LLC (US) 2018-06-21 US claimed
US-8747875-B2 Photo-stable pest control THE HARTZ MOUNTAIN CORPORATION (US) 2014-06-10 US claimed
US-20110224296-A1 PHOTO-STABLE PEST CONTROL THE HARTZ MOUNTAIN CORPORATION 2011-09-15 US claimed
WO-2010036882-A1 PHOTO-STABLE PEST CONTROL THE HARTZ MOUNTAIN CORPORATION (US) 2010-04-01 WO claimed
WO-2009059064-A1 A LONG-ACTING, WATERPROOF OR WATER-RESISTANT, TOPICAL SUN PROTECTION AGENT WITH ACTIVITY UP TO WEEKS SPHJK, INC. (US) 2009-05-07 WO claimed